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Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by PRPF4B is thought to be involved in pre-mRNA splicing and in signal transduction. Additionally we are shipping Serine/threonine-Protein Kinase PRP4 Homolog Antibodies (62) and many more products for this protein.
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PRP4K is novel estrogen regulated kinase, and its levels can be reduced by 4-OHT in ER+ breast cancer cells altering their response to taxanes
PRP4K functions as a HER2 (show ERBB2 Proteins)-regulated modifier of taxane sensitivity and is a prognostic biomarker for better survival in taxane-treated ovarian cancer patients. PRP4K knock-down results in "mitotic slippage" in response to taxanes, and reduced PRP4K expression is associated with both intrinsic and acquired resistance of ovarian and breast cancers to taxanes.
data indicate that miR (show MLXIP Proteins)-371-5p, which is highly expressed in hepatocellular carcinoma, promotes the growth of HCC (show FAM126A Proteins) cells in vitro and in vivo by activating cell cycle progression at the G1/S checkpoint by directly targeting PRPF4B
The authors provide evidence that PRP6 (show PRPF6 Proteins) and PRP31 (show PRPF31 Proteins) are directly phosphorylated by human PRP4 kinase (PRP4K) concomitant with their incorporation into B complexes.
Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: PRPF4B.
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP (show LSM2 Proteins) and the N-CoR (show NCOR1 Proteins) deacetylase complexes.
PRP4, a serine/threonine protein kinase (show PRKACG Proteins), is identified as a Kruppel-like factor 13 (KLF13 (show KLF13 Proteins))-binding protein; PRP4 phosphorylates KLF13 (show KLF13 Proteins)
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).
, PRP4 pre-mRNA-processing factor 4 homolog
, dJ1013A10.1 (PRP4 protein kinase homolog)
, protein-serine/threonine kinase
, serine/threonine-protein kinase PRP4 homolog
, pre-mRNA protein kinase
, PRP4 pre-mRNA processing factor 4 homolog B
, serine/threonine-protein kinase PRP4K
, PRP4 pre-mRNA processing factor 4 homolog B (yeast)