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Serine/arginine Repetitive Matrix 1 Proteins (SRRM1)

Part of pre- and post-splicing multiprotein mRNP complexes. Additionally we are shipping SRRM1 Antibodies (27) and SRRM1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRRM1 10250 Q8IYB3
SRRM1 51796 Q52KI8
Rat SRRM1 SRRM1 313620  
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Top SRRM1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SRRM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Serine/arginine Repetitive Matrix 1 (SRRM1) Interaction Partners

Human Serine/arginine Repetitive Matrix 1 (SRRM1) interaction partners

  1. 1H, 13C, and 15N resonance assignments and secondary structure of the PWI (show WRB Proteins) domain from SRm160 was determined using reduced dimensionality NMR.

  2. Proto-oncoprotein TLS/FUS (show FUS Proteins) is associated to the nuclear matrix and complexed with splicing factors PTB (show PTBP1 Proteins), SRm160, and SR proteins and plays a role in spliceosome assembly

  3. two contiguous sequences that independently target SRm160 to nuclear matrix sites at splicing speckled domains: amino acids 300-350 and 351-688

  4. Data show that SRm160, a splicing coactivator and component of the exon junction complex (EJC) involved in RNA export, has an adenosine triphosphate (ATP)-dependent mobility.

  5. found that the majority of proteins identified in SRm160-containing complexes are associated with pre-mRNA processing (show PRPF39 Proteins). Interestingly, SRm160 is also associated with factors involved in chromatin regulation and sister chromatid cohesion

  6. SRm160, a splicing coactivator, regulates CD44 alternative splicing in a Ras-dependent manner.

SRRM1 Protein Profile

Protein Summary

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates (By similarity).

Gene names and symbols associated with SRRM1

  • serine/arginine repetitive matrix 1 (SRRM1)
  • serine/arginine repetitive matrix 1 (Srrm1)
  • 160-KD protein
  • AA407769 protein
  • POP101 protein
  • Srm160 protein

Protein level used designations for SRRM1

SR-related nuclear matrix protein of 160 kDa , Ser/Arg-related nuclear matrix protein , serine/arginine repetitive matrix protein 1 , plenty-of-prolines 101 , plenty-of-prolines-101

GENE ID SPECIES
10250 Homo sapiens
51796 Mus musculus
428216 Gallus gallus
478185 Canis lupus familiaris
100521629 Sus scrofa
784123 Bos taurus
313620 Rattus norvegicus
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