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anti-Serine/arginine Repetitive Matrix 4 (SRRM4) Antibodies

SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009].. Additionally we are shipping SRRM4 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRRM4 84530 A7MD48
SRRM4 68955 Q8BKA3
SRRM4 498189  
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Top anti-SRRM4 Antibodies at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot showing SRRM4 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details

SRRM4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Mouse (Murine)


Rat (Rattus)


More Antibodies against SRRM4 Interaction Partners

Human Serine/arginine Repetitive Matrix 4 (SRRM4) interaction partners

  1. The splicing of REST by SRRM4 could promote the neuroendocrine phenotype in CRPC.

  2. Neural microexons are regulated by the neuronal-specific splicing factor (show SLU7 Antibodies) nSR100/SRRM4, through its binding to adjacent intronic enhancer motifs; neural microexons are frequently misregulated in the brains of individuals with autism spectrum disorder, and this misregulation is associated with reduced levels of nSR100.

  3. findings show that nSR100 plays a role in the alternative splicing of REST in small cell lung cancer (SCLC); study provides new insight into the role of nSR100 in the expression of sREST, possibly in the pathogenesis of SCLC

Mouse (Murine) Serine/arginine Repetitive Matrix 4 (SRRM4) interaction partners

  1. Loss of nSR100 impairs development of the central and peripheral nervous systems in part by disrupting neurite outgrowth, cortical layering in the forebrain, and axon guidance in the corpus callosum

  2. findings show that nSR100 plays a role in the alternative splicing of REST in small cell lung cancer (SCLC); study provides new insight into the role of nSR100 in the expression of sREST, possibly in the pathogenesis of SCLC

  3. required for the continued survival and differentiation of inner and vestibular hair cells past a set point in their development

  4. Srrm4 function is critical in the hearing and balance organs, but not in all neural tissues. Srrm4 is the first alternative-splicing regulator (show PTBP2 Antibodies) to be associated with hearing. Analysis of bv mice provides exon-level insights into hair-cell development.

  5. role for nSR100 in the inhibition of REST activity, blocking nSR100 expression in the developing mouse brain impairs neurogenesis

  6. Study identified the neural-specific SR-related protein of 100 kDa (nSR100)& shows that nSR100 regulates an extensive network of brain-specific (show CALY Antibodies) alternative exons enriched in genes that function in neural cell differentiation.

SRRM4 Antigen Profile

Protein Summary

SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009

Gene names and symbols associated with SRRM4

  • serine/arginine repetitive matrix 4 (SRRM4) antibody
  • serine/arginine repetitive matrix 4 (Srrm4) antibody
  • serine/arginine repetitive matrix 4 (srrm4) antibody
  • 1500001A10Rik antibody
  • B230202K19Rik antibody
  • im:7136231 antibody
  • KIAA1853 antibody
  • mKIAA1853 antibody
  • MU-MB-2.76 antibody
  • nSR100 antibody
  • RGD1560213 antibody
  • si:dkey-1k23.1 antibody
  • SRRM2C antibody
  • ZnSR100 antibody

Protein level used designations for SRRM4

medulloblastoma antigen MU-MB-2.76 , neural-specific SR-related protein of 100 kDa , neural-specific serine/arginine repetitive splicing factor of 100 kDa , serine/arginine repetitive matrix protein 4 , KIAA1853 protein-like , serine/arginine repetitive matrix 2C , serine/arginine repetitive matrix 4 , Neural-specific serine/arginine repetitive splicing factor of 100 kDa

GENE ID SPECIES
84530 Homo sapiens
416989 Gallus gallus
611405 Canis lupus familiaris
614115 Bos taurus
68955 Mus musculus
498189 Rattus norvegicus
796574 Danio rerio
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