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Serine/threonine Kinase Receptor Associated Protein Proteins (STRAP)

The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. Additionally we are shipping STRAP Antibodies (48) and STRAP Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STRAP 11171 Q9Y3F4
STRAP 20901 Q9Z1Z2
Rat STRAP STRAP 297699 Q5XIG8
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Top STRAP Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,951.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STRAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Serine/threonine Kinase Receptor Associated Protein (STRAP) Interaction Partners

Human Serine/threonine Kinase Receptor Associated Protein (STRAP) interaction partners

  1. MAWD and MAWBP (show PBLD Proteins) were downregulated and associated with the differentiation grade in GC tissues.

  2. STRAP inhibits the transactivation function of Sp1 either by directly blocking its DNA binding domain or destabilizing Sp1 protein through ubiquitin-proteasome pathway in cell cycle G1 phase.

  3. Strap augments the apoptotic effects of mitochondrial p53 (show TP53 Proteins).

  4. Coexpression of MAWBP (show PBLD Proteins) and MAWD inhibited epithelial mesenchymal transformation, and EMT (show ITK Proteins)-aided malignant cell progression was suppressed in gastric cancer.

  5. Data indicate serine-threonine kinase receptor-associated protein (STRAP) as a novel regulator of the coordinated translation of collagen alpha1(I) and alpha2(I (show COL1A2 Proteins)) mRNAs.

  6. both of the TPR and OB-fold domains localize to the chromatin of p53 (show TP53 Proteins) target genes and exhibit intrinsic regulatory activity necessary for the Strap-dependent p53 (show TP53 Proteins) response

  7. STRAP protein decreases ubiquitination of intracellular domain of Notch3 (show NOTCH3 Proteins) and may help to stabilize it.

  8. B-MYB (show MYBL2 Proteins) acts as a positive regulator of STRAP

  9. gonucleotide pulldown identified STRAP (serine/threonine kinase receptor-associated protein) as a further protein recruited to the MMP28 (show MMP28 Proteins) promoter and acting functionally with Sp1 (show PSG1 Proteins).

  10. STRAP can act as a negative regulator of ASK1 (show MAP3K5 Proteins).

Mouse (Murine) Serine/threonine Kinase Receptor Associated Protein (STRAP) interaction partners

  1. STRAP Ser (show SIGLEC1 Proteins)(188) phosphorylation in the liver is tightly associated with cell death and proliferation through ASK1 (show MAP3K5 Proteins), TGF-beta (show TGFB1 Proteins), p53 (show TP53 Proteins), and PI3K/PDK1 (show PDPK1 Proteins) pathways, resulting in apoptotic cell death.

  2. Data indicate serine-threonine kinase receptor-associated protein (STRAP) as a novel regulator of the coordinated translation of collagen alpha1(I) and alpha2(I (show COL1A2 Proteins)) mRNAs.

  3. both of the TPR (show GRID2 Proteins) and OB-fold domains localize to the chromatin of p53 (show TP53 Proteins) target genes and exhibit intrinsic regulatory activity necessary for the Strap-dependent p53 (show TP53 Proteins) response

  4. STRAP regulates c-Jun (show JUN Proteins) stability by decreasing the ubiquitylation and proteosomal degradation of c-Jun (show JUN Proteins).

  5. Gemin8 (show GEMIN8 Proteins) has an essential role in the proper structural organization of the SMN (show STMN1 Proteins) complex and the involvement of the heteromeric subunit containing Gemin6 (show GEMIN6 Proteins), Gemin7 (show GEMIN7 Proteins), Gemin8 (show GEMIN8 Proteins), and Unrip in the recruitment of Sm proteins to the snRNP (show LSM2 Proteins) assembly pathway

  6. NM23-H1 (show NME1 Proteins) and its interacting partner STRAP physically interact with p53 (show TP53 Proteins) and positively regulate its functions, including p53 (show TP53 Proteins)-induced apoptosis and cell cycle arrest

STRAP Protein Profile

Protein Summary

The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein (By similarity).

Gene names and symbols associated with STRAP

  • serine/threonine kinase receptor associated protein (strap)
  • serine/threonine kinase receptor associated protein (STRAP)
  • serine/threonine kinase receptor associated protein (Strap)
  • AW557906 protein
  • C78091 protein
  • C79202 protein
  • MAWD protein
  • PT-WD protein
  • Unrip protein
  • zgc:56677 protein
  • zgc:77604 protein

Protein level used designations for STRAP

serine-threonine kinase receptor-associated protein , MAP activator with WD repeats , WD-40 repeat protein PT-WD , unr-interacting protein , UNR-interacting protein

GENE ID SPECIES
393274 Danio rerio
779439 Xenopus laevis
11171 Homo sapiens
486663 Canis lupus familiaris
510201 Bos taurus
20901 Mus musculus
297699 Rattus norvegicus
418175 Gallus gallus
465315 Pan troglodytes
Selected quality suppliers for STRAP Proteins (STRAP)
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