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Serine/threonine Kinase 19, Pseudogene 1 Proteins (STK19-PS1)

The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. Additionally we are shipping Serine/threonine Kinase 19, Pseudogene 1 Antibodies (32) and Serine/threonine Kinase 19, Pseudogene 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STK19-PS1 6102 O75695
Rat STK19-PS1 STK19-PS1 140662 P02401
Mouse STK19-PS1 STK19-PS1 114241  
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Top Serine/threonine Kinase 19, Pseudogene 1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Baculovirus infected Insect Cells Human GST tag 100 μg Log in to see 16 Days
$822.80
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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STK19-PS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,

More Proteins for Serine/threonine Kinase 19, Pseudogene 1 (STK19-PS1) Interaction Partners

Human Serine/threonine Kinase 19, Pseudogene 1 (STK19-PS1) interaction partners

  1. study also reveals a role of the C-terminal domain of RP2 (show NUDT19 Proteins) in maintaining the overall protein stability.

  2. Three XLRP families (RP-001, RP-002, and RP-003), composed of 13 individuals, were reported in this study, and 2 different mutations were detcted We found 3 genetic variants: a novel mutation c.1591G>T in exon 14 and a novel polymorphism c.1105C>T in exon 10, resulting in p.Glu531* and p.Arg369Cys of RPGR (show RPGR Proteins) gene, respectively, and one already known mutation c.413A>G in exon 2, resulting in a p.Glu138Gly of RP2 (show NUDT19 Proteins) gene

  3. We identified a novel causative mutation in RP2 (show NUDT19 Proteins) from a single proband's exome sequence data analysis. This study highlights the effectiveness of the whole-exome sequencing in the genetic diagnosis of X-linked retinitis pigmentosa, over the conventional sequencing methods.

  4. Three mutations were identified in the ORF15 (show RPGR Proteins) exon of RPGR (show RPGR Proteins). No RP2 (show NUDT19 Proteins) mutations were found among the examined families. Mutation screening of RP patients is essential to understand the mechanism behind this disease and develop treatments

  5. seven out of 27 families, displaying mutations in the ABCA4, RP1, RP2 and USH2A genes, could be genetically or clinically reclassified. These results demonstrate the potential of our panel-based NGS strategy in RP diagnosis

  6. The ability of the restored RP2 protein (show P2RX1 Proteins) level to reverse the observed cellular phenotypes in cells lacking RP2 (show NUDT19 Proteins) indicates that translational read-through could be clinically beneficial for patients.

  7. ellipsometric measurements of naRP2 demonstrated that its particular affinity for saturated phospholipids can be explained by its larger extent of insertion in this phospholipid monolayer compared to that in polyunsaturated phospholipid monolayers.

  8. The methylation state of CpG sites close to the RP2 (show NUDT19 Proteins) core promoter (GAAA)n repeat serves as a proxy measurement of X-chromosome inactivation in human and non-human primates.

  9. A novel frameshift mutation in RP2 (show NUDT19 Proteins) was detected. This mutation was located in exon 2 of the RP2 (show NUDT19 Proteins) gene: a nucleotide C was inserted at 111 (c.111insC, Fig. 1A), which caused a protein translation frameshift

  10. Direct sequencing of RPGR (show RPGR Proteins) and RP2 (show NUDT19 Proteins) allowed for identification of a disease-causing mutation in 21 families. Of these "adRP (show PLIN2 Proteins)" families 19 had RPGR (show RPGR Proteins) mutations, and two had RP2 (show NUDT19 Proteins) mutations.

Serine/threonine Kinase 19, Pseudogene 1 (STK19-PS1) Protein Profile

Protein Summary

The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death

Gene names and symbols associated with STK19-PS1

  • retinitis pigmentosa 2 (X-linked recessive) (RP2)
  • ribosomal protein, large P2 (Rplp2)
  • serine/threonine kinase 19, pseudogene 1 (Stk19-ps1)
  • DELXp11.3 protein
  • NM23-H10 protein
  • NME10 protein
  • RP2 protein
  • TBCCD2 protein
  • XRP2 protein

Protein level used designations for STK19-PS1

protein XRP2 , 60S acidic ribosomal protein P2 , ribosomal protein P2

GENE ID SPECIES
6102 Homo sapiens
140662 Rattus norvegicus
114241 Mus musculus
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