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The product of MST4 is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. Additionally we are shipping Serine/threonine-Protein Kinase MST4 Proteins (4) and and many more products for this protein.
Showing 10 out of 55 products:
Human Polyclonal MST4 Primary Antibody for ELISA, WB - ABIN249471
Dan, Ong, Watanabe, Blagoev, Nielsen, Kajikawa, Kristiansen, Mann, Pandey: Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties. in The Journal of biological chemistry 2002
Findings reveal a mechanism by which TRAF6 (show TRAF6 Antibodies) is regulated and highlight a role for MST4 in limiting inflammatory responses.
Low MST-4 expression is associated with Graves' disease.
these data identify the MST4 kinase as a novel candidate to mediate human pituitary tumorigenesis in a hypoxic environment and position it as a potential therapeutic target.
Our results suggest that MST4, STK25 (show STK25 Antibodies) and PDCD10 (show PDCD10 Antibodies) are upregulated in prostate cancer and may play roles in prostate tumorigenesis. MST4 may be a helpful marker for identifying prostate cancer.
This study describes the key role of MST4 in facilitating the epithelial-mesenchymal transition process in hepatocellular carcinoma
Mutation of this residue was sufficient to switch the phosphorylation site preference for multiple kinases, including the serine-specific kinase PAK4 (show PAK4 Antibodies) and the threonine-specific kinase MST4.
CCM3 (show PDCD10 Antibodies) forms a stable complex with MST4 in vivo to promote cell proliferation and migration synergistically in a manner dependent on MST4 kinase activity.
In this review, the germinal center kinase (show MAP4K2 Antibodies) III subfamily of mammalian Ste20 (show STK24 Antibodies) (sterile 20)-like group of serine/threonine protein kinases comprises Ste20-like (show STK25 Antibodies)/oxidant-stress-response kinase 1, MST3 (show STK24 Antibodies) mammalian Ste20-like kinase 3 (show STK24 Antibodies) and MST4.
crystal of the CCM3 (show PDCD10 Antibodies)-MST4 C-terminal domain complex belonged to space group P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters a = 69.10, b = 69.10, c = 117.57 A
MST4 expression in prostate carcinoma tumor samples & cell lines correlated with tumorigenicity & AR status. Overexpression induced anchorage-independent growth & tumorigenesis.It may have a role in the signal transduction in prostate cancer progression.
The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
, Mst3 and SOK1-related kinase
, STE20-like kinase MST4
, mammalian STE20-like protein kinase 4
, serine/threonine protein kinase MST4
, serine/threonine-protein kinase MST4
, mammalian Ste20-like protein kinase 4
, mammalian sterile 20-like 4
, serine/threonine-protein kinase MASK