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Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by PRPF4B is thought to be involved in pre-mRNA splicing and in signal transduction. Additionally we are shipping Serine/threonine-Protein Kinase PRP4 Homolog Antibodies (62) and Serine/threonine-Protein Kinase PRP4 Homolog Proteins (6) and many more products for this protein.
PRP4K is novel estrogen regulated kinase, and its levels can be reduced by 4-OHT in ER+ breast cancer cells altering their response to taxanes
PRP4K functions as a HER2 (show ERBB2 ELISA Kits)-regulated modifier of taxane sensitivity and is a prognostic biomarker for better survival in taxane-treated ovarian cancer patients. PRP4K knock-down results in "mitotic slippage" in response to taxanes, and reduced PRP4K expression is associated with both intrinsic and acquired resistance of ovarian and breast cancers to taxanes.
The p.R192H variant of PRPF4 (show PRPF4 ELISA Kits) represents a functional null allele which compromises the function of the tri (show VANGL2 ELISA Kits)-snRNP (show LSM2 ELISA Kits), reinforcing the notion that this spliceosomal particle is of crucial importance in the physiology of the retina.
PRPF4 (show PRPF4 ELISA Kits) missense mutations is associated with autosomal dominant retinitis pigmentosa.
the requirement of enzymatic activity of PRP4 in regulating cancer cell growth and identified an array of potential novel substrates through orthogonal proteomics approaches
data indicate that miR (show MLXIP ELISA Kits)-371-5p, which is highly expressed in hepatocellular carcinoma, promotes the growth of HCC (show FAM126A ELISA Kits) cells in vitro and in vivo by activating cell cycle progression at the G1/S checkpoint by directly targeting PRPF4B
The authors provide evidence that PRP6 (show PRPF6 ELISA Kits) and PRP31 (show PRPF31 ELISA Kits) are directly phosphorylated by human PRP4 kinase (PRP4K) concomitant with their incorporation into B complexes.
Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: PRPF4B.
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP (show LSM2 ELISA Kits) and the N-CoR (show NCOR1 ELISA Kits) deacetylase complexes.
PRP4, a serine/threonine protein kinase, is identified as a Kruppel-like factor 13 (KLF13 (show KLF13 ELISA Kits))-binding protein; PRP4 phosphorylates KLF13 (show KLF13 ELISA Kits)
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).
PRP4 pre-mRNA processing factor 4 homolog B
, serine/threonine-protein kinase PRP4 homolog
, PRP4 pre-mRNA-processing factor 4 homolog
, PRP4 pre-mRNA processing factor 4 homolog B (yeast)
, PRP4 homolog
, PRP4/STK/WD splicing factor
, U4/U6 small nuclear ribonucleoprotein Prp4
, U4/U6 snRNP 60 kDa protein
, WD splicing factor Prp4
, PRP4 kinase
, dJ1013A10.1 (PRP4 protein kinase homolog)
, protein-serine/threonine kinase
, pre-mRNA protein kinase
, serine/threonine-protein kinase PRP4K