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Serotonin Receptor 2C Proteins (HTR2C)

Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. Additionally we are shipping Serotonin Receptor 2C Antibodies (47) and Serotonin Receptor 2C Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HTR2C 15560 P34968
HTR2C 3358 P28335
Rat HTR2C HTR2C 25187 P08909
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Top Serotonin Receptor 2C Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HTR2C Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Serotonin Receptor 2C (HTR2C) Interaction Partners

Mouse (Murine) Serotonin Receptor 2C (HTR2C) interaction partners

  1. results demonstrate that CHL1 regulates signal transduction pathways through constitutively active 5-HT2c receptor isoforms, thereby altering 5-HT2c receptor functions and implicating CHL1 as a new modulator of the serotonergic system.

  2. Social Behavioral Deficits Coincide with the Onset of Seizure Susceptibility in Mice Lacking Serotonin Receptor 2c.

  3. This study showed that reduced expression of the 5ht1c which modulate antidepressant action in hippocampus.

  4. Suppressed feeding behavior in novelty stress-exposed aged male mice may be mediated by 5-HT(2C)R hypersensitivity, leading to hypoghrelinemia. The hypersensitivity may partly be due to estrogen receptor (show ESR1 Proteins) activation in aged male mice.

  5. Results show that mice solely expressing the unedited INI (show PHF5A Proteins) form of 5-HT2C receptors exhibit a hyperactive HPA (show HPSE Proteins) axis driven by increased CRH (show CRH Proteins), a normal response to chronic stress and decreased depressive-like behaviors and fear-associated memory

  6. Chronic intermittent ethanol upregulates 5HT2C receptor signaling in the bed nucleus of the stria terminalis.

  7. findings show that enhanced alcohol drinking behaviour in mice is associated with the degree of 5-HT(2C)R mRNA editing in the nucleus accumbens and dorsal raphe nuceus

  8. Precise temporal control of Gq signals in 5-HT2c-R domains in GABAergic neurons upstream of 5-HT (show DDC Proteins) neurons provides negative feedback regulation of serotonergic firing to modulate anxiety-like behavior in mice.

  9. Results of the current study suggest aggression displayed by TLX null and heterozygous mice involves 5-HT(2A/C) receptors.

  10. Mice lacking Htr2c specifically in POMC (show POMC Proteins) neurons had normal weight but developed glucoregulatory defects: hyperinsulinemia, hyperglucagonemia, hyperglycemia, & insulin (show INS Proteins) resistance. These neurons are needed to control energy & glucose homeostasis.

Human Serotonin Receptor 2C (HTR2C) interaction partners

  1. the occurrence of hyperprolactinemia, although asymptomatic, was higher in the presence of the C allele of the rs6318 SNP of the HTR2C gene.

  2. SLC6A14 (show Slc6a14 Proteins) and 5-HTR2C polymorphisms are associated with food intake and nutritional status in children.

  3. RNA element is discovered, which coordinates site-specific RNA editing on HTR2C pre-mRNA by an in vitro editing assay and secondary structural analysis of mutant HTR2C RNA fragments.

  4. No significant differences were found between the genotype distribution and allele frequencies of the OSAHS group and the control group regarding the T102C polymorphisms of the 5-HTR (show F2R Proteins) 2A gene and the G796C polymorphisms of the 5-HTR (show F2R Proteins) 2C gene.

  5. Results of the present study do not support a major role of SNPs of HTR2C rs1414334 in the regulation of weight gain or association of serum levels in patients with schizophrenia on clozapine treatment.

  6. ADARB1 rs9983925 and rs4819035 and HTR2C rs6318 were associated with suicide attempt risk.

  7. A functional SNP on the HTR2C gene may confer an increased risk for depressive symptoms in White women with a history of significant life stress.

  8. Activation of 5-HT2C receptor promotes neprilysin (show MME Proteins) expression in glioma cells.

  9. These findings validate our initial observation of association between functional nonsynonymous single nucleotide polymorphism rs6318 on the HTR2C gene and cortisol response to an acute stressor, and extend the results to include females.

  10. found the lack of an association between 5-HT2C Cys (show DNAJC5 Proteins)/Ser (show SIGLEC1 Proteins) variants and the risk of bipolar I disorder in Kurds population.

Pig (Porcine) Serotonin Receptor 2C (HTR2C) interaction partners

  1. although the expression of the long transcriptional variant of HTR2C is raised in infanticidal animals, the overall patterns of editing in the hypothalamus are similar between the two states.

Serotonin Receptor 2C (HTR2C) Protein Profile

Protein Summary

Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with Serotonin Receptor 2C Proteins (HTR2C)

  • serotonin receptor 2C (5ht2c)
  • 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c)
  • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C)
  • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (Htr2c)
  • 5-hydroxytryptamine 2C receptor (5htr2c)
  • 5-HT-2C protein
  • 5-HT2C protein
  • 5-HT2cR protein
  • 5-HTR2C protein
  • 5HT-1C protein
  • 5HT1c protein
  • 5ht2c protein
  • 5HTR2C protein
  • HTR1C protein
  • SR1 protein

Protein level used designations for Serotonin Receptor 2C Proteins (HTR2C)

serotonin receptor 2C , 5-HT-1C , 5-HT-2C , 5-HT1C , 5-HT2C receptor , 5-hydroxytryptamine receptor 1C , 5-hydroxytryptamine receptor 2C , 5-hydroxytryptamine receptor-1c , serotonin 5-HT-2C receptor , 5-HT2C , serotonin 1c receptor , 5-alpha-hydroxytryptamine receptor 2C

GENE ID SPECIES
100169693 Cavia porcellus
15560 Mus musculus
3358 Homo sapiens
450240 Canis lupus familiaris
25187 Rattus norvegicus
100524920 Sus scrofa
473740 Pan troglodytes
407134 Bos taurus
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