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Serotonin Receptor 3A Proteins (HTR3A)

The product of HTR3A belongs to the ligand-gated ion channel receptor superfamily. Additionally we are shipping Serotonin Receptor 3A Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HTR3A 15561 P23979
HTR3A 3359 P46098
Rat HTR3A HTR3A 79246 P35563
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Top Serotonin Receptor 3A Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

HTR3A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
,

More Proteins for Serotonin Receptor 3A (HTR3A) Interaction Partners

Mouse (Murine) Serotonin Receptor 3A (HTR3A) interaction partners

  1. found the protein levels of AMPA (show GRIA3 Proteins) receptor subunits (GluR1 (show GRIA1 Proteins) and GluR2 (show GRIA2 Proteins)) are upregulated in the amygdala and the 5-HT3 receptor is downregulated in hypothalamic regions of Socially Isolated mice.

  2. The data of this study demonstrated that the 5-HT3 receptor is the critical target of 5-HT (show DDC Proteins) action in exercise-induced hippocampal neurogenesis and antidepressant effects, but not in learning enhancement.

  3. The deletion of Htr3a was related to fatal arrhythmias and sudden cardiac death during pregnancy, and its activation reversed the QT prolongation.

  4. The results of this study suggested that 5-HT (show DDC Proteins) released from type III cells activates gustatory nerve fibers via 5-HT3 receptors, accounting for a significant proportion of the neural taste response.

  5. Htr3a is required for controlling the migration and laminar positioning of reelin (show RELN Proteins)-expressing interneurons in the neocortex.

  6. Deletion of the 5-HT3AR gene in transgenic mice abolished N-methyl-d-aspartate (NMDA) receptor (NMDAR)-dependent long-term depression (LTD) induced by low-frequency stimulation (LFS) in hippocampal CA1 (show CA1 Proteins) synapses in slices.

  7. Results indicate that vestibular ganglion cells express functional 5-HT3 receptor channels (with 5-HT3a and 5-HT3b (show HTR3B Proteins) subunits) and might play a modulatory role in the peripheral vestibular nervous system

  8. 5-HT (show DDC Proteins) system in the small intestine may play a critical role in regulating circadian rhythms through 5-HT3/5-HT4 (show HTR4 Proteins)-receptor activation.

  9. X-ray structure of a mammalian Cys (show DNAJC5 Proteins)-loop receptor, the mouse serotonin 5-HT3 receptor, at 3.5 A resolution

  10. The data of this study suggested that the 5-HT3A receptor could be a key molecule regulating fear memory processes and a potential therapeutic target for fear disorders.

Human Serotonin Receptor 3A (HTR3A) interaction partners

  1. Alternative Viewpoint Against Breast Cancer Based on Selective Serotonin Receptors 5HTR3A and 5HTR2A Antagonists that can Mediate Apoptosis in MCF-7 Cell Line

  2. A gene-environment interaction is revealed between childhood trauma and 5-htr3a polymorphisms.

  3. 5-HT3A receptor distal targeting in axons and dendrites depends on P2X2R expression.

  4. Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors

  5. Data indicate that no two n-alkanols act alike, their spectra of effects on serotonin receptor 3A (5-HT3A) receptors differ.

  6. Our findings support the notion that different haplotypes of HTR3A have reciprocal effects in the etiology of Postoperative nausea.

  7. HTR3A gene variants may contribute to variability in severity of and response to antiemetic therapy for nausea and vomiting of pregnancy.

  8. These data support a role for intracellular salt bridges in maintaining the quaternary structure of the 5-HT3 receptor and suggest a role for the intracellular domain in allosteric modulation of cooperativity and agonist efficacy.

  9. Data suggest that HTR3A/HTR3B (show HTR3B Proteins) subunits readily form functionally distinct heteromeric receptors; molecular models have been developed regarding affinities of competitive ligands, non-competitive antagonists, and allosteric modulators. [REVIEW]

  10. A significant increase in the relative expression level of 5-HT (show DDC Proteins)(3A) receptor in PBMCs.

Serotonin Receptor 3A (HTR3A) Protein Profile

Protein Summary

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Serotonin Receptor 3A Proteins (HTR3A)

  • 5-hydroxytryptamine (serotonin) receptor 3A (htr3a)
  • 5-hydroxytryptamine (serotonin) receptor 3A (HTR3A)
  • 5-hydroxytryptamine (serotonin) receptor 3A (Htr3a)
  • 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic (HTR3A)
  • 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic (Htr3a)
  • 5-HT-3 protein
  • 5-HT3 protein
  • 5-HT3A protein
  • 5-HT3R protein
  • 5HT3 protein
  • 5HT3R protein
  • Htr3 protein
  • HTR3A protein
  • MGC52789 protein

Protein level used designations for Serotonin Receptor 3A Proteins (HTR3A)

5-hydroxytryptamine (serotonin) receptor 3A , 5-hydroxytryptamine receptor 3A , 5-HT3 receptor , 5-hydroxytryptamine receptor 3A-like , 5-HT-3 , 5-HT3-A , 5-HT3A , 5-HT3R , 5-hydroxytryptamine receptor 3 , 5HT3 serotonin receptor , serotonin receptor 3A , serotonin-gated ion channel receptor , 5-HT3-Al receptor , 5-hydroxytryptamine type 3A receptor

GENE ID SPECIES
379233 Xenopus laevis
428247 Gallus gallus
451556 Pan troglodytes
617674 Bos taurus
100009570 Oryctolagus cuniculus
100009690 Equus caballus
100032164 Monodelphis domestica
100402630 Callithrix jacchus
100447353 Pongo abelii
100477001 Ailuropoda melanoleuca
100541887 Meleagris gallopavo
100599162 Nomascus leucogenys
100625131 Sus scrofa
15561 Mus musculus
100135547 Cavia porcellus
3359 Homo sapiens
79246 Rattus norvegicus
489399 Canis lupus familiaris
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