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anti-Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) Antibodies

SERPINF2 encodes a member of the serpin family of serine protease inhibitors. Additionally we are shipping SERPINF2 Kits (6) and SERPINF2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINF2 18816 Q61247
SERPINF2 5345 P08697
SERPINF2    
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Top anti-SERPINF2 Antibodies at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry: Serpin F2/alpha 2-Antiplasmin Antibody [ABIN4091156] - IHC staining of Alpha 2 Antiplasmin in paraffin embedded Human Liver using ABIN4091156 at 3.8ug/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Alpha 2 Antiplasmin Antibody [NBP1-90305] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: Alpha 2 Antiplasmin Antibody [NBP1-90305] - Staining of human liver shows moderate cytoplasmic and nuclear positivity in hepatocytes. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated WB   100 μg Log in to see 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated WB   0.1 mg Log in to see 6 to 9 Days
$490.88
Details
Mouse Rat Un-conjugated WB   0.1 mg Log in to see 6 to 9 Days
$490.88
Details
Human Rabbit Un-conjugated   100 μg Log in to see 9 to 16 Days
$474.38
Details
Mouse Rabbit Un-conjugated   100 μg Log in to see 9 to 16 Days
$474.38
Details
Rat Rabbit Un-conjugated   100 μg Log in to see 9 to 16 Days
$488.13
Details

SERPINF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)
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Human
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Rat (Rattus)

Top referenced anti-SERPINF2 Antibodies

  1. Human Polyclonal SERPINF2 Primary Antibody for IHC (p), IHC - ABIN409115 : Lee, Jackson, Christiansen, Chung, McKee: A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion. in Blood 2004 (PubMed)
    Show all 2 references for ABIN409115

  2. Human Polyclonal SERPINF2 Primary Antibody for IHC, IHC (p) - ABIN4352973 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

More Antibodies against SERPINF2 Interaction Partners

Mouse (Murine) Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Antibodies) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Alpha 2 antiplasmin is involved in the recruitment of lymphocytes in the peripheral tissues.Alpha 2 antiplasmin contributes to the maintenance of immunological functions that are related to IgE.

  3. Plasmin (show PLG Antibodies)/alpha(2)-AP system played an important role in hepatic repair via clearance from the injury area.

  4. PgtE mediated degradation of the antiprotease alpha(2)-antiplasmin leads to functional inactivation of the antiprotease in infected macrophages

  5. alpha2-antiplasmin induction inhibits E-cadherin (show CDH1 Antibodies) processing mediated by the plasminogen (show PLG Antibodies) activator/plasmin (show PLG Antibodies) system, leading to suppression of progression of oral squamous cell carcinoma via upregulation of cell-cell adhesion

  6. The lack of alpha2AP attenuated TGF-beta(1 (show TGFB1 Antibodies)) synthesis, thereby resulting in attenuated fibrosis

  7. 2.65A X-ray crystal structure of an N-terminal truncated murine alpha(2)-antiplasmin.

  8. Results show that alpha2-antiplasmin is a critical regulator for vascular remodeling by inhibiting p53 (show TP53 Antibodies)/p21 (show D4S234E Antibodies) pathway.

Human Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

  1. alpha2AP has a profibrotic effect probably not by the action as a plasmin (show PLG Antibodies) inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis

  2. Possession of the alpha2AP 407Lys allele was negatively associated with AAA (show APP Antibodies), and thus changes in alpha2AP may affect aneurysm growth and development.

  3. Two differentially expressed proteins, alpha-1-antitrypsin (SERPINA1) and alpha-2 antiplasmin (SERPINF2) are associated with purpura fulminans.

  4. Data suggest serum A2AP (SERPINF2) level can serve as biomarker for diabetic retinopathy; levels of A2AP (but not fibrinogen, plasminogen (show PLG Antibodies), or plasminogen activator inhibitor 1 (show SERPINE1 Antibodies)) are up-regulated in hyperglycemic type 1 diabetes with retinopathy.

  5. Study revealed that plasmin (show PLG Antibodies) was present in tumor tissue, and that it was responsible for processing progalanin to galanin (show GAL Antibodies)(1-20) in the extracellular environment.

  6. Data suggest that decreased amounts of alpha2-plasmin (show PLG Antibodies) inhibitor in plasma vs serum ex vivo may reflect reduced factor XIII (show UGDH Antibodies) (FXIII) in vivo; thus, plasma vs serum alpha2-plasmin (show PLG Antibodies) inhibitor may be useful diagnostic marker for severe FXIII deficiency.

  7. When the C terminus of alpha(2)-antiplasmin was removed, the binding affinity for active site-blocked plasmin (show PLG Antibodies) remained high, suggesting additional exosite interactions between the serpin core and plasmin (show PLG Antibodies).

  8. Truncation of monocyte chemoattractant protein 1 (show CCL2 Antibodies) by plasmin (show PLG Antibodies) promotes blood-brain barrier disruption.

  9. ADAMTS13 (show ADAMTS13 Antibodies) inactivation by plasmin (show PLG Antibodies) as a potential cause of thrombotic thrombocytopenic purpura

  10. Results describe the functional characterization of the unique plasmin (show PLG Antibodies)(ogen)-binding region of the human alpha(2)-plasmin inhibitor.

Rabbit Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 2 (SERPINF2) interaction partners

SERPINF2 Antigen Profile

Protein Summary

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SERPINF2

  • serine (or cysteine) peptidase inhibitor, clade F, member 2 (Serpinf2) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2) antibody
  • A2AP antibody
  • AAP antibody
  • AI747498 antibody
  • ALPHA-2-PI antibody
  • API antibody
  • PLI antibody
  • Serpimf2 antibody
  • serpin antibody

Protein level used designations for SERPINF2

alpha 2 antiplasmin , alpha-2-AP , alpha-2-PI , alpha-2-antiplasmin , alpha-2-plasmin inhibitor , pigment epithelium derived factor , plasmin inhibitor alpha 2 , serine (or cysteine) proteinase inhibitor, clade F, member 2 , serpin F2 , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 , alpha-2-PI serine protease inhibitor

GENE ID SPECIES
18816 Mus musculus
5345 Homo sapiens
100009515 Oryctolagus cuniculus
282522 Bos taurus
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