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SAA1 encodes a member of the serum amyloid A family of apolipoproteins. Additionally we are shipping SAA1 Antibodies (188) and SAA1 Proteins (61) and many more products for this protein.
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Human SAA1 ELISA Kit for Sandwich ELISA - ABIN414457
Ma, Luo, Wu, Chen, Kou, Wang: Circulation levels of acute phase proteins in patients with Takayasu arteritis. in Journal of vascular surgery 2010
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Mouse (Murine) SAA1 ELISA Kit for Sandwich ELISA - ABIN424092
Peh, Anwar, Ng, Atan, Kumar, Moore: Effect of feeding a high fat diet on hydrogen sulfide (H2S) metabolism in the mouse. in Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2014
Show all 2 references for ABIN424092
Eren, Ellidag, Y?lmaz, Ayd?n, Y?lmaz: No association between vitamin D levels and inflammation markers in patients with acute coronary syndrome. in Advances in medical sciences 2015
SAA inhibits osteoclast formation from mouse macrophages. SAA blocks RANKL (show TNFSF11 ELISA Kits)-induced osteoclastogenesis.
Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.
These data demonstrate that SAA stimulates a robust pro-inflammatory response in skeletal muscle myotubes via the TLR2 (show TLR2 ELISA Kits)-dependent release of IL-6 (show IL6 ELISA Kits) and TNFalpha (show TNF ELISA Kits).
Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL (show HSD11B1 ELISA Kits)
SAA1/2 produced by macrophages promotes early lesion formation in the ascending aorta in LDLR (show LDLR ELISA Kits) knockout mice.
Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 ELISA Kits) via TLR2 (show TLR2 ELISA Kits) and directly synergizes with this chemokine (show CCL1 ELISA Kits) via CXCR2 (show CXCR2 ELISA Kits) and formyl peptide receptor 2 (show FPR2 ELISA Kits) to recruit neutrophils.
Robust IL-17A (show IL17A ELISA Kits) production was restricted to the ileum, where SFB (show CEBPB ELISA Kits) makes direct contact with the epithelium and induces serum amyloid A proteins 1 and 2 (SAA1/2), which promote local IL-17A (show IL17A ELISA Kits) expression in RORgammat(+) T17 cells.
SAA protein levels increased in both serum and lung within 2-24h after mice were exposed to Aspergillus spores. SAA mRNA levels increased within the first hour after mice were exposed to A. fumigatus.
Saa1 might be a novel inflammatory factor that acts as a chemokine (show CCL1 ELISA Kits) modulator in hepatitis.
Zn deficiency enhances the acute phase response and particularly the JAK-STAT3 pathway, resulting in increased serum amyloid A production.
Structure, function and SAA1 gene polymorphisms
Amyloid A overexpressed in renal cell carcinoma patients and can serve as a prognostic marker.
incorporation of SAA into HDL (show HSD11B1 ELISA Kits) preparations reduced antiinflammatory properties but not to the same extent as HDL (show HSD11B1 ELISA Kits) from AgNO3-injected mice
human SAA is possibly only expressed in a subset of septic patients; SAA induces HMGB1 (show HMGB1 ELISA Kits) release via TLR4 (show TLR4 ELISA Kits) and RAGE (show AGER ELISA Kits) receptors; SAA supplementation worsens the outcome of lethal endotoxemia
The SAA1 rs12218 polymorphism was significantly more prevalent in ankylosing spondylitis patients with amyloidosis.
Autocrine/paracrine and recombinant human SAA1 via TLR4 (show TLR4 ELISA Kits) stimulate a proinflammatory phenotype that is both part of the early phase of osteogenic differentiation and the development of senescence.
These functional properties set SAA apart from well-characterized inflammatory factors, such as LPS (show IRF6 ELISA Kits) and TNF-alpha (show TNF ELISA Kits), suggesting that it may play a homeostatic role during the course of inflammation.
The detailed analysis of the docking results points to the fact that the best serum amyloid A-Cystatin C (show CST3 ELISA Kits) (SAA-hCC (show FAM126A ELISA Kits)) binding is achieved by the peptides inclined toward interacting via Lys90 and Arg 96 (with ffhCC Ser98 and Tyr102, respectively).
polymorphisms in the SAA2 gene are associated with milk production traits in Chinese Holstein cows
endometritis gives rise to a systemic acute phase response and an up-regulated endometrial gene expression of SAA and several pro-and anti-inflammatory cytokines
The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
serum amyloid A protein
, serum amyloid A1
, serum amyloid a protein
, serum amyloid A 2
, serum amyloid A-1 protein
, serum amyloid A
, serum amyloid A-3 protein
, tumor protein p53 inducible protein 4
, serum amyloid A2