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Serum Amyloid A1 Proteins (SAA1)

SAA1 encodes a member of the serum amyloid A family of apolipoproteins. Additionally we are shipping SAA1 Antibodies (189) and SAA1 Kits (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SAA1 20208 P05366
SAA1 6288 P0DJI8
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Top SAA1 Proteins at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$242.00
Details
Yeast Horse His tag Serum Amyloid A1 (SAA1) (AA 1-110), (full length) protein (His tag) 500 μg Log in to see 56 to 66 Days
$1,155.00
Details
HOST_Escherichia coli (E. coli) Human His tag Serum Amyloid A1 (SAA1) (AA 20-122), (full length) protein (His tag) 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Cat His tag,B2M 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Dog HIS-GST 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Horse His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Horse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details

SAA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , , ,
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Top referenced SAA1 Proteins

  1. Human SAA1 Protein expressed in Escherichia coli (E. coli) - ABIN666889 : Betts, Edbrooke, Thakker, Woo: The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells. in Scandinavian journal of immunology 1991 (PubMed)
    Show all 2 references for ABIN666889

More Proteins for Serum Amyloid A1 (SAA1) Interaction Partners

Mouse (Murine) Serum Amyloid A1 (SAA1) interaction partners

  1. SAA inhibits osteoclast formation from mouse macrophages. SAA blocks RANKL (show TNFSF11 Proteins)-induced osteoclastogenesis.

  2. Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.

  3. These data demonstrate that SAA stimulates a robust pro-inflammatory response in skeletal muscle myotubes via the TLR2-dependent release of IL-6 (show IL6 Proteins) and TNFalpha (show TNF Proteins).

  4. Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL (show HSD11B1 Proteins)

  5. SAA1/2 produced by macrophages promotes early lesion formation in the ascending aorta in LDLR (show LDLR Proteins) knockout mice.

  6. Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Proteins) via TLR2 and directly synergizes with this chemokine (show CCL1 Proteins) via CXCR2 (show CXCR2 Proteins) and formyl peptide receptor 2 (show FPR2 Proteins) to recruit neutrophils.

  7. Robust IL-17A (show IL17A Proteins) production was restricted to the ileum, where SFB (show CEBPB Proteins) makes direct contact with the epithelium and induces serum amyloid A proteins 1 and 2 (SAA1/2), which promote local IL-17A (show IL17A Proteins) expression in RORgammat(+) T17 cells.

  8. SAA protein levels increased in both serum and lung within 2-24h after mice were exposed to Aspergillus spores. SAA mRNA levels increased within the first hour after mice were exposed to A. fumigatus.

  9. Saa1 might be a novel inflammatory factor that acts as a chemokine (show CCL1 Proteins) modulator in hepatitis.

  10. Zn deficiency enhances the acute phase response and particularly the JAK-STAT3 pathway, resulting in increased serum amyloid A production.

Human Serum Amyloid A1 (SAA1) interaction partners

  1. Structure, function and SAA1 gene polymorphisms

  2. Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.

  3. Amyloid A overexpressed in renal cell carcinoma (show MOK Proteins) patients and can serve as a prognostic marker.

  4. incorporation of SAA into HDL (show HSD11B1 Proteins) preparations reduced antiinflammatory properties but not to the same extent as HDL (show HSD11B1 Proteins) from AgNO3-injected mice

  5. human SAA is possibly only expressed in a subset of septic patients; SAA induces HMGB1 (show HMGB1 Proteins) release via TLR4 (show TLR4 Proteins) and RAGE (show AGER Proteins) receptors; SAA supplementation worsens the outcome of lethal endotoxemia

  6. The SAA1 rs12218 polymorphism was significantly more prevalent in ankylosing spondylitis patients with amyloidosis.

  7. Autocrine/paracrine and recombinant human SAA1 via TLR4 (show TLR4 Proteins) stimulate a proinflammatory phenotype that is both part of the early phase of osteogenic differentiation and the development of senescence.

  8. Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Proteins) via TLR2 and directly synergizes with this chemokine (show CCL1 Proteins) via CXCR2 (show CXCR2 Proteins) and formyl peptide receptor 2 (show FPR2 Proteins) to recruit neutrophils.

  9. These functional properties set SAA apart from well-characterized inflammatory factors, such as LPS (show IRF6 Proteins) and TNF-alpha (show TNF Proteins), suggesting that it may play a homeostatic role during the course of inflammation.

  10. The detailed analysis of the docking results points to the fact that the best serum amyloid A-Cystatin C (SAA-hCC) binding is achieved by the peptides inclined toward interacting via Lys90 and Arg 96 (with ffhCC Ser98 and Tyr102, respectively).

Cow (Bovine) Serum Amyloid A1 (SAA1) interaction partners

  1. polymorphisms in the SAA2 gene are associated with milk production traits in Chinese Holstein cows

Horse (Equine) Serum Amyloid A1 (SAA1) interaction partners

  1. endometritis gives rise to a systemic acute phase response and an up-regulated endometrial gene expression of SAA and several pro-and anti-inflammatory cytokines

  2. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.

SAA1 Protein Profile

Protein Summary

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.

Gene names and symbols associated with Serum Amyloid A1 Proteins (SAA1)

  • serum amyloid A1 (SAA1)
  • serum amyloid A (saa)
  • serum amyloid A protein (Sden_2438)
  • serum amyloid A protein (Mmc1_0571)
  • serum amyloid a protein (Riean_0971)
  • serum amyloid A 1 (Saa1)
  • serum amyloid A cluster (Saa)
  • serum amyloid A-3 (SAA3)
  • serum amyloid A-like 1 (SAAL1)
  • serum amyloid A1 (SAA)
  • serum amyloid A2 (SAA2)
  • serum amyloid protein A (LOC100009168)
  • PIG4 protein
  • SAA protein
  • Saa-1 protein
  • SAA1 protein
  • SAA2 protein
  • TP53I4 protein
  • zgc:103580 protein

Protein level used designations for Serum Amyloid A1 Proteins (SAA1)

serum amyloid A protein , saa1 , serum amyloid A1 , serum amyloid a protein , serum amyloid A 2 , serum amyloid A-1 protein , serum amyloid A , serum amyloid A-3 protein , tumor protein p53 inducible protein 4 , serum amyloid A2

GENE ID SPECIES
403585 Canis lupus familiaris
449557 Danio rerio
480749 Canis lupus familiaris
751814 Canis lupus familiaris
4018937 Shewanella denitrificans OS217
4481493 Magnetococcus marinus MC-1
10001727 Riemerella anatipestifer ATCC 11845 = DSM 15868
20208 Mus musculus
111345 Mus musculus
100009138 Oryctolagus cuniculus
100341988 Oryctolagus cuniculus
6288 Homo sapiens
616035 Bos taurus
678660 Felis catus
100033905 Equus caballus
476879 Canis lupus familiaris
100034017 Equus caballus
694827 Macaca mulatta
506412 Bos taurus
100009168 Oryctolagus cuniculus
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