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anti-Sestrin 1 (SESN1) Antibodies

SESN1 encodes a member of the sestrin family. Additionally we are shipping Sestrin 1 Kits (9) and Sestrin 1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SESN1 27244 Q9Y6P5
SESN1 140742 P58006
SESN1 294518  
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Top anti-Sestrin 1 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of Sestrin-1 antibody (C-term) (ABIN391992) in mouse heart tissue lysates (35 µg/lane). Sestrin-1 (arrow) was detected using the purified polyclonal antibody. Sestrin-1 Antibody (C-term) (ABIN391992) western blot analysis in NCI-H460,HL-60 cell line lysates (35 µg/lane).This demonstrates the Sestrin-1 antibody detected the Sestrin-1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from rat muscle cells, using SESN1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SESN1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Sestrin-1 Antibody (N-term) (ABIN652375) in mouse heart tissue lysates (35 µg/lane). Sestrin-1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Sesn1 AntibodyTitration: 1.0 µg/mL  Positive Control: Rat Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of SESN1 expression in transfected 293T cell line by SESN1 MaxPab polyclonal antibody.Lane 1: SESN1 transfected lysate(60.61 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to SESN1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SESN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sestrin 1 Antibodies

  1. Human Polyclonal SESN1 Primary Antibody for EIA, WB - ABIN492723 : Budanov, Karin: p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. in Cell 2008 (PubMed)
    Show all 7 references for ABIN492723

  2. Human Polyclonal SESN1 Primary Antibody for FACS, WB - ABIN391992 : Budanov, Sablina, Feinstein, Koonin, Chumakov: Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 3 references for ABIN391992

  3. Human Polyclonal SESN1 Primary Antibody for IHC, ELISA - ABIN1535359 : Velasco-Miguel, Buckbinder, Jean, Gelbert, Talbott, Laidlaw, Seizinger, Kley: PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes. in Oncogene 1999 (PubMed)
    Show all 2 references for ABIN1535359

  4. Human Polyclonal SESN1 Primary Antibody for WB - ABIN652375 : Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. in Genes & development 2015 (PubMed)

  5. Human Polyclonal SESN1 Primary Antibody for IF, WB - ABIN525920 : Renna, Bento, Fleming, Menzies, Siddiqi, Ravikumar, Puri, Garcia-Arencibia, Sadiq, Corrochano, Carter, Brown, Acevedo-Arozena, Rubinsztein: IGF-1 receptor antagonism inhibits autophagy. in Human molecular genetics 2013 (PubMed)

More Antibodies against Sestrin 1 Interaction Partners

Zebrafish Sestrin 1 (SESN1) interaction partners

  1. identify SESN1 as an indispensable gene for vertebrate left-right asymmetry and a new player in mediating Nodal signaling

Human Sestrin 1 (SESN1) interaction partners

  1. Rapamycin may prohibit sestrin1 downregulation through targeting mTORC2 (show CRTC2 Antibodies) in appeasing low shear stress induced EC oxidative apoptosis

  2. PA26 mutations are an infrequent cause of heterotaxia (situs inversus) in humans.

  3. results show that sestrins, a family of proteins whose expression is modulated by p53 (show TP53 Antibodies), are required for regeneration of peroxiredoxins containing Cys (show DNAJC5 Antibodies)-SO(2)H

Mouse (Murine) Sestrin 1 (SESN1) interaction partners

  1. Study found that Sestrins (1,2 and 3) can inhibit mTORC1 signaling in the absence of AMPK (show PRKAA1 Antibodies) or TSC2 (show TSC2 Antibodies). Surprisingly, when coexpressed with a GTP (show AK3 Antibodies)-bound constitutively active form of RagB (show RRAGB Antibodies) (RagBQ99L), Sestrins potentiate mTORC1 signaling in the absence of amino acids.

  2. The enhanced tumor susceptibility of p53 (show TP53 Antibodies)+/- mice has made them one of several transgenic mouse models that are being considered as substitutes for standard 2-year rodent carcinogenicity assays.

  3. Sestrin1 and Sestrin2 therefore provide an important link between genotoxic stress, p53 (show TP53 Antibodies) and the mTOR (show FRAP1 Antibodies) signaling pathway.

Sestrin 1 (SESN1) Antigen Profile

Protein Summary

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with anti-Sestrin 1 (SESN1) Antibodies

  • sestrin 1 (SESN1) antibody
  • sestrin 1 (sesn1) antibody
  • sestrin 1 (Sesn1) antibody
  • 1110002G11Rik antibody
  • AU044290 antibody
  • Pa26 antibody
  • SESN1 antibody
  • sesn1-A antibody
  • Sest1 antibody
  • sestrin-1 antibody
  • XPA26 antibody
  • zgc:91970 antibody

Protein level used designations for anti-Sestrin 1 (SESN1) Antibodies

sestrin 1 , sestrin-1 , nuclear factor XPA26-T2 , p53 activated gene 26 , p53 regulated PA26 nuclear protein , p53 regulated Pa26 nuclear protein , p53-regulated protein PA26 , XPA26 , sestrin 1,nuclear factor XPA26-T2

GENE ID SPECIES
421766 Gallus gallus
436933 Danio rerio
462922 Pan troglodytes
481956 Canis lupus familiaris
700232 Macaca mulatta
100170187 Xenopus (Silurana) tropicalis
100174188 Pongo abelii
100601789 Nomascus leucogenys
27244 Homo sapiens
140742 Mus musculus
294518 Rattus norvegicus
538226 Bos taurus
379559 Xenopus laevis
Selected quality suppliers for anti-Sestrin 1 (SESN1) Antibodies
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