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Sex Hormone Binding Globulin Proteins (SHBG)

SHBG encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. Additionally we are shipping Sex Hormone Binding Globulin Antibodies (190) and Sex Hormone Binding Globulin Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SHBG 20415 P97497
SHBG 24775 P08689
SHBG 6462 P04278
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Top Sex Hormone Binding Globulin Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Human Human Un-conjugated   100 μg Log in to see 7 to 9 Days
$617.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$563.20
Details
Yeast REACT_Spotted hyena His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,004.83
Details
Yeast Phodopus sungorus His tag   1 mg Log in to see 56 to 66 Days
$3,014.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$739.20
Details

SHBG Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus) ,

Human , ,
,

Top referenced Sex Hormone Binding Globulin Proteins

  1. Human SHBG Protein expressed in Human - ABIN934692 : Hauptmann, Metzger, Schnitzbauer, Cuilleron, Mappus, Luppa: Syntheses and ligand-binding studies of 1 alpha- and 17 alpha-aminoalkyl dihydrotestosterone derivatives to human sex hormone-binding globulin. in Steroids 2003 (PubMed)

More Proteins for Sex Hormone Binding Globulin (SHBG) Interaction Partners

Zebrafish Sex Hormone Binding Globulin (SHBG) interaction partners

  1. characterization of the zebrafish SHBG gene and protein through molecular biological, biochemical, and informatics approaches

  2. SHBG controls the flux of sex steroids across fish.

Mouse (Murine) Sex Hormone Binding Globulin (SHBG) interaction partners

  1. A wave of apoptosis during the pre-pubertal period is required for normal spermatogenesis to develop, and our data indicate that this apoptotic wave may be regulated by ABP and/or androgens.

  2. USF transcription factors repress SHBG transcription in Sertoli cells through an interaction with FP4 within its proximal promoter

  3. monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha (show HNF4A Proteins) levels, which in turn attenuated SHBG expression.

Human Sex Hormone Binding Globulin (SHBG) interaction partners

  1. There was a drop in SHBG levels in the first week of smoking cessation and levels continued to remain low.

  2. SHBG was higher in both obese and non-obese PCOS patients compared to healthy controls.

  3. Specific SHBG variants affecting serum SHBG levels and SHBG haplotypes are associated with polycystic ovary syndrome, suggesting the role for SHBG as polycystic ovary syndrome candidate gene.

  4. overlapping of interacting amino acid residues between phthalate compounds and natural ligand, dihydrotestosterone, suggested potential disrupting activity of phthalates in the endocrine homeostasis function of SHBG

  5. Data suggest that, in endurance runners using endurance training followed by strength training, an initial reduction in testosterone/SHBG ratio is seen after 12 weeks followed by large increase in weeks 12-24 (as compared to endurance training alone).

  6. SHBG levels were lower in women with polycystic ovary syndrome compared to controls.

  7. the TAAAA repeat polymorphism was shown to not be a major determinant of the PCOS status, although it influenced serum SHBG levels in females with PCOS.

  8. SHBG overexpression reduced weight gain but did not change the metabolic profile of obese mice. SHBG down-regulation during obesity development involved changes in liver HNF4alpha (show HNF4A Proteins) and PPARgamma (show PPARG Proteins) mRNA and protein levels.

  9. prognostic role of testosterone in men with type 2 diabetes mellitus (T2DM) is influenced by its carrier protein sex hormone-binding globulin

  10. data suggest that higher SHBG levels are associated with worse verbal memory.

Cow (Bovine) Sex Hormone Binding Globulin (SHBG) interaction partners

  1. Three novel mutations with very damaging effect on the protein structure, according to SIFT and Polyphen-2, were detected in GART, SHBG and SLC37A2 genes.

Sex Hormone Binding Globulin (SHBG) Protein Profile

Protein Summary

This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SHBG

  • sex hormone binding globulin (shbg)
  • sex hormone binding globulin (Shbg)
  • sex hormone-binding globulin (SHBG)
  • sex hormone-binding globulin (Shbg)
  • sex hormone-binding globulin-like (LOC100856157)
  • ABP protein
  • Abpa protein
  • SBP protein
  • shbgl protein
  • TEBG protein
  • wu:fb66h07 protein
  • wu:fd55b08 protein
  • zgc:123063 protein

Protein level used designations for SHBG

cb991 , SBP , sex hormone-binding globulin , sex steroid-binding protein , testis-specific androgen-binding protein , ABP , Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene) , testosterone-binding beta-globulin , testosterone-estradiol-binding globulin , testosterone-estrogen-binding globulin , androgen binding protein 1 (296 AA) , sex hormone binding globulin , sex hormone-binding globulin protein

GENE ID SPECIES
322604 Danio rerio
20415 Mus musculus
24775 Rattus norvegicus
6462 Homo sapiens
100009224 Oryctolagus cuniculus
100734981 Cavia porcellus
479487 Canis lupus familiaris
404182 Bos taurus
100511959 Sus scrofa
101102995 Ovis aries
100856157 Canis lupus familiaris
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