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SHISA5 encodes a member of the shisa family. Additionally we are shipping Shisa Homolog 5 (Xenopus Laevis) Antibodies (30) and Shisa Homolog 5 (Xenopus Laevis) Proteins (8) and many more products for this protein.
IFN-beta (show IFNB1 ELISA Kits)-induced SCOTIN recruits the HCV NS5A protein to autophagosomes for degradation, thereby restricting HCV replication.
Scotin plays a role in p53 (show TP53 ELISA Kits)-dependent apoptosis
ALG-2 (show PDCD6 ELISA Kits) binding to Scotin is strictly calcium dependent, indicating a role of this interaction in calcium signaling pathways
We conclude that Scotin is a new p63 (show CKAP4 ELISA Kits) target gene induced during epithelial differentiation, a complex process that also involves ER stress induction.
Mouse Scotin induces apoptosis and developmental defects when overexpressed in Drosophila.
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants.
, putative NF-kappa-B-activating protein 120
, shisa homolog 5