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Sialic Acid Binding Ig-Like Lectin 11 Proteins (SIGLEC11)

SIGLEC11 encodes a member of the sialic acid-binding immunoglobulin-like lectin family. Additionally we are shipping SIGLEC11 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SIGLEC11 114132 Q96RL6
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Top SIGLEC11 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details

SIGLEC11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11) Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11) interaction partners

  1. The results indicate potential roles for Siglec-11 in ovarian physiology and human evolution.

  2. Siglec-11 ectopically expressed on murine microglia interacts with PSA (show PLAG1 Proteins) on neurons, reduces LPS (show IRF6 Proteins)-induced gene transcription of proinflammatory mediators, impairs phagocytosis and alleviates microglial neurotoxicity.

  3. cloning and characterization; a recently evolved signaling that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages including brain microglia

  4. expressed in human but not in chimpanzee brain microglia; findings indicate that human SIGLEC11 emerged through human-specific gene conversion by an adjacent pseudogene

  5. SIGLEC16 encodes a DAP12 (show TYROBP Proteins)-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.

SIGLEC11 Protein Profile

Protein Summary

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SIGLEC11

  • sialic acid binding Ig-like lectin 11 (SIGLEC11)

Protein level used designations for SIGLEC11

sialic acid-binding Ig-like lectin 11 , siglec-11 , sialic acid binding Ig-like lectin 11 , sialic acid-binding Ig-like lectin 11-like

GENE ID SPECIES
114132 Homo sapiens
747721 Pan troglodytes
100387822 Callithrix jacchus
100447534 Pongo abelii
100605002 Nomascus leucogenys
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