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Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) ELISA Kits

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. Additionally we are shipping SIGLEC12 Antibodies (50) and SIGLEC12 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIGLEC12 89858 Q96PQ1
SIGLEC12 83382 Q91Y57
SIGLEC12    
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Top SIGLEC12 ELISA Kits at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 100-2500 pg/mL 96 Tests Log in to see 11 to 13 Days
$785.71
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Mouse
96 Tests Log in to see 8 to 9 Days
$680.63
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Pig
96 Tests Log in to see 8 to 9 Days
$770.00
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Chicken
96 Tests Log in to see 8 to 9 Days
$770.00
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Rabbit
96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
96 Tests Log in to see 8 to 9 Days
$770.00
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Guinea Pig
96 Tests Log in to see 8 to 9 Days
$770.00
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Rat
96 Tests Log in to see 11 to 13 Days
$785.71
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Goat
96 Tests Log in to see 11 to 13 Days
$801.43
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Dog
96 Tests Log in to see 11 to 13 Days
$801.43
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More ELISA Kits for SIGLEC12 Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) interaction partners

  1. cardiovascular outcomes may differ based on SIGLEC12 genotype, and antihypertensive treatment strategy.

  2. SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas.

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 12 (Gene/pseudogene) (SIGLEC12) interaction partners

  1. indicate that Siglec-9 (show SIGLEC9 ELISA Kits) affects several different signaling pathways in IL-4 (show IL4 ELISA Kits)-stimulated macrophages, which resulted in enhanced induction of Arg1 (show ARG1 ELISA Kits) in Siglec-9 (show SIGLEC9 ELISA Kits)-expressing RAW264 cells

  2. Competitive ELISA assays confirmed the involvement of sulfated (show SULF1 ELISA Kits) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  3. Data indicate a role for neuraminidase 1 (Neu1 (show NEU1 ELISA Kits)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 ELISA Kits)) interaction and endotoxemia.

  4. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (show CD33 ELISA Kits)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  5. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (show NOX1 ELISA Kits) activation and ROS (show ROS1 ELISA Kits) production

  6. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (show MUC1 ELISA Kits)-expressing tumor in the transgenic mice.

  7. Siglec-9 (show SIGLEC9 ELISA Kits) expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 ELISA Kits) and that this signaling may be another MUC1 (show MUC1 ELISA Kits)-mediated pathway and function in parallel with a growth factor-dependent pathway.

  8. Siglec-E is induced in a MyD88 (show MYD88 ELISA Kits)-dependent manner. Once up-regulated, it can control TLR-dependent NF-kappaB (show NFKB1 ELISA Kits) antiviral responses by directly inhibiting TLR-induced antiviral cytokine production.

SIGLEC12 Antigen Profile

Antigen Summary

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.

Gene names and symbols associated with SIGLEC12

  • sialic acid binding Ig-like lectin 12 (SIGLEC12) antibody
  • sialic acid binding Ig-like lectin 12 (gene/pseudogene) (SIGLEC12) antibody
  • sialic acid binding Ig-like lectin 12-like (LOC618463) antibody
  • sialic acid binding Ig-like lectin E (Siglece) antibody
  • Cd170 antibody
  • mSiglec-E antibody
  • S2V antibody
  • Siglec-XII antibody
  • Siglec5 antibody
  • Siglec9 antibody
  • Siglec12 antibody
  • Siglecl1 antibody
  • SLG antibody

Protein level used designations for SIGLEC12

SIGLEC-like 1 , sialic acid binding immunoglobulin-like lectin-like protein 1 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding lectin Siglec-L1 , siglec-12 , siglec-L1 , sialic acid binding Ig-like lectin 12 , MIS , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin E , sialic acid-binding immunoglobulin-like lectin E , siglec-5 , siglec-E

GENE ID SPECIES
484344 Canis lupus familiaris
450120 Pan troglodytes
89858 Homo sapiens
618463 Bos taurus
83382 Mus musculus
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