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Putative adhesion molecule. Additionally we are shipping SIGLEC14 Proteins (5) and many more products for this protein.
Showing 10 out of 32 products:
Human Polyclonal SIGLEC14 Primary Antibody for EIA, WB - ABIN954805
Yamanaka, Kato, Angata, Narimatsu: Deletion polymorphism of SIGLEC14 and its functional implications. in Glycobiology 2009
Show all 3 references for ABIN954805
An unbiased screen revealed Hsp70 (show HSP70 Antibodies) as a ligand for Siglec-5 (show SIGLEC5 Antibodies) and Siglec-14. Hsp70 (show HSP70 Antibodies) stimulation through Siglec-5 (show SIGLEC5 Antibodies) delivers an anti-inflammatory signal, while stimulation through Siglec-14 is pro-inflammatory.
Genome-wide association analyses revealed common DNA variants in PLG (show PLG Antibodies), LPA (show APOA Antibodies), and near SIGLEC14 that contribute to plasma plasminogen (show PLG Antibodies) level variation.
Data indicate that the Siglec-5 (show SIGLEC5 Antibodies)/14 genotype influences neutrophil responses to group B Streptococcus.
Siglec-14 and its downstream signaling pathway facilitate the "infection-inflammation-exacerbation" axis of COPD (show ARCN1 Antibodies) disease progression
Siglec-14 and Siglec-5 (show SIGLEC5 Antibodies) appear to be the first glycan binding paired receptors. Near-complete sequence identity of the amino-terminal part of human Siglec-14 and Siglec-5 (show SIGLEC5 Antibodies) indicates partial gene conversion between SIGLEC14 and SIGLEC5 (show SIGLEC5 Antibodies).
The presence of the "SIGLEC14 null" allele in all human populations we tested implies an ancient origin, while its allelic frequency is higher in Asians compared with Africans and Europeans. Siglec-14 may play some role in bacterial infection.
Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
sialic acid-binding Ig-like lectin 14