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Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) ELISA Kits

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Additionally we are shipping SIGLEC9 Antibodies (131) and SIGLEC9 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIGLEC9 27180 Q9Y336
Anti-Mouse SIGLEC9 SIGLEC9 83382 Q91Y57
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Top SIGLEC9 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 31.25 pg/ml 8000-125 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for SIGLEC9 Interaction Partners

Chimpanzee Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) interaction partners

  1. Binding studies on recombinant human Siglec-9 show recognition of both Neu5Ac and Neu5Gc; in striking contrast, chimpanzee and gorilla Siglec-9 strongly prefer binding Neu5Gc.

Human Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) interaction partners

  1. Ligands for Siglec-8 (show SIGLEC8 ELISA Kits) and Siglec-9 may regulate the function of eosinophils, mast cells, neutrophils, and other cells in sinus mucosa.

  2. Inflammation results in up-regulation of immuneinhibitory Siglec-8 (show SIGLEC8 ELISA Kits) and Siglec-9 sialoglycan ligands on human airways.

  3. a polymorphism that reduced Siglec-9 binding to carcinomas was associated with improved early survival in non-small-cell lung ca (show CD33 ELISA Kits)ncer patients

  4. Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3 (show CD33 ELISA Kits).

  5. Expression of Siglec-7 (show SIGLEC7 ELISA Kits) and -9 ligands was associated with susceptibility of NK cell-sensitive tumor cells and, unexpectedly, of presumably NK cell-resistant tumor cells to NK cell-mediated cytotoxicity.

  6. Protein degradation of focal adhesion kinase and related molecules was induced by Siglec-9 binding to its counterreceptors via sialylglycoconjugates, leading to the modulation of adhesion kinetics of cancer cells.

  7. Siglec-9 expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 ELISA Kits) and that this signaling may be another MUC1 (show MUC1 ELISA Kits)-mediated pathway and function in parallel with a growth factor-dependent pathway.

  8. The Siglec-9 peptide binding to the enzymatic groove of VAP-1 (show AOC3 ELISA Kits) can be used for imaging conditions, such as inflammation and cancer.

  9. Siglec-9 A391C was the only polymorphism related to TCR-mediated signaling in human Siglec-9, resulting in less inhibition compared to the wild type.

  10. These results suggest that Siglec-9 expressed on DCs is involved in immunoregulation through ligation with mucins in an epithelial cancer patient.

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9) interaction partners

  1. indicate that Siglec-9 affects several different signaling pathways in IL-4 (show IL4 ELISA Kits)-stimulated macrophages, which resulted in enhanced induction of Arg1 (show ARG1 ELISA Kits) in Siglec-9-expressing RAW264 cells

  2. Competitive ELISA assays confirmed the involvement of sulfated (show SULF1 ELISA Kits) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  3. Data indicate a role for neuraminidase 1 (Neu1 (show NEU1 ELISA Kits)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 ELISA Kits)) interaction and endotoxemia.

  4. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (show CD33 ELISA Kits)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  5. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (show NOX1 ELISA Kits) activation and ROS (show ROS1 ELISA Kits) production

  6. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (show MUC1 ELISA Kits)-expressing tumor in the transgenic mice.

  7. Siglec-9 expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 ELISA Kits) and that this signaling may be another MUC1 (show MUC1 ELISA Kits)-mediated pathway and function in parallel with a growth factor-dependent pathway.

  8. Siglec-E is induced in a MyD88 (show MYD88 ELISA Kits)-dependent manner. Once up-regulated, it can control TLR-dependent NF-kappaB (show NFKB1 ELISA Kits) antiviral responses by directly inhibiting TLR-induced antiviral cytokine production.

SIGLEC9 Antigen Profile

Antigen Summary

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Gene names and symbols associated with SIGLEC9

  • sialic acid-binding immunoglobulin-like lectin 9 (siglec9) antibody
  • sialic acid binding Ig-like lectin 9 (SIGLEC9) antibody
  • sialic acid binding Ig-like lectin E (Siglece) antibody
  • Cd170 antibody
  • CD329 antibody
  • CDw329 antibody
  • FOAP-9 antibody
  • mSiglec-E antibody
  • OBBP-LIKE antibody
  • siglec-9 antibody
  • Siglec5 antibody
  • Siglec9 antibody
  • Siglec12 antibody
  • Siglecl1 antibody

Protein level used designations for SIGLEC9

sialic acid-binding immunoglobulin-like lectin 9 , sialic acid binding Ig-like lectin 9 , protein FOAP-9 , sialic acid-binding Ig-like lectin 9 , MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-5 , siglec-E , siglec-L1

GENE ID SPECIES
497116 Pan troglodytes
100610476 Pan troglodytes
27180 Homo sapiens
83382 Mus musculus
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