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anti-Sialic Acid Binding Ig-Like Lectin E (Siglece) Antibodies

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Siglece 83382 Q91Y57
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Top anti-Siglece Antibodies at

Showing 2 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Goat Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
Mouse Rat FITC FACS, IP   50 μg Log in to see 8 to 10 Days

Siglece Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
, ,

More Antibodies against Siglece Interaction Partners

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin E (Siglece) interaction partners

  1. Data indicate a role for neuraminidase 1 (Neu1 (show NEU1 Antibodies)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) interaction and endotoxemia.

  2. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (show CD33 Antibodies)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  3. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (show NOX1 Antibodies) activation and ROS (show ROS1 Antibodies) production

  4. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (show MUC1 Antibodies)-expressing tumor in the transgenic mice.

  5. Siglec-9 (show SIGLEC9 Antibodies) expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 Antibodies) and that this signaling may be another MUC1 (show MUC1 Antibodies)-mediated pathway and function in parallel with a growth factor-dependent pathway.

  6. Siglec-E is induced in a MyD88 (show MYD88 Antibodies)-dependent manner. Once up-regulated, it can control TLR-dependent NF-kappaB (show NFKB1 Antibodies) antiviral responses by directly inhibiting TLR-induced antiviral cytokine production.

Siglece Antigen Profile

Protein Summary

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Gene names and symbols associated with Siglece

  • sialic acid binding Ig-like lectin E (Siglece) antibody
  • Cd170 antibody
  • mSiglec-E antibody
  • Siglec5 antibody
  • Siglec9 antibody
  • Siglec12 antibody
  • Siglecl1 antibody

Protein level used designations for Siglece

MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-5 , siglec-E , siglec-L1

83382 Mus musculus
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