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Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Additionally we are shipping Sialic Acid Binding Ig-Like Lectin 7 Proteins (11) and Sialic Acid Binding Ig-Like Lectin 7 Kits (6) and many more products for this protein.
Showing 10 out of 216 products:
Human Polyclonal SIGLEC7 Primary Antibody for EIA, IHC (p) - ABIN357158
Nicoll, Avril, Lock, Furukawa, Bovin, Crocker: Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. in European journal of immunology 2003
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Human Polyclonal SIGLEC7 Primary Antibody for EIA, IHC (p) - ABIN357160
Alphey, Attrill, Crocker, van Aalten: High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family. in The Journal of biological chemistry 2003
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Human Monoclonal SIGLEC7 Primary Antibody for FACS - ABIN2476485
Dahlin: Aspects on pathophysiology of nerve entrapments and nerve compression injuries. in Neurosurgery clinics of North America 1992
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Human Polyclonal SIGLEC7 Primary Antibody for WB - ABIN2782808
Jaroenpool, Rogers, Pattanapanyasat, Villinger, Onlamoon, Crocker, Ansari: Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates. in Cellular immunology 2008
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Human Polyclonal SIGLEC7 Primary Antibody for FACS, IHC - ABIN4899406
Izquierdo-Useros, Lorizate, Puertas, Rodriguez-Plata, Zangger, Erikson, Pino, Erkizia, Glass, Clotet, Keppler, Telenti, Kräusslich, Martinez-Picado: Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides. in PLoS biology 2012
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Cow (Bovine) Polyclonal SIGLEC7 Primary Antibody for WB - ABIN2782809
Braun: The T-cell receptor: just another hypothesis. in Cellular immunology 1976
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Siglec-7 defines a highly functional natural killer cell subset and inhibits cell-mediated activities.
Siglec-7 plays a significant role in inhibiting IgE-mediated mast cell activation, but only moderately affects IgE-mediated activation in primary human basophils.
These results show that Siglec-7 binds HIV-1 via gp120 (show ITIH4 Antibodies) and contributes to enhance the susceptibility to infection of CD4 (show CD4 Antibodies) positive T cells and monocyte-derived macrophages.
Expression of Siglec-7 and -9 ligands was associated with susceptibility of NK cell-sensitive tumor cells and, unexpectedly, of presumably NK cell-resistant tumor cells to NK cell-mediated cytotoxicity.
Based on upregulated SIGLEC7 expression in blood monocytes during relapse, findings suggest a role for SIGLEC7 in acute disease activity in multiple sclerosis.
Siglec-7 participates in generating a monocyte-mediated inflammatory outcome following pathogen recognition.
Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 (show CD33 Antibodies) surface receptors.
Sialidase unmasking of siglec-7 on NK cells permits it to interact with GD3 on target cells and inhibit killing. This has inplications for tumor escape from NK cells.
x-ray crystallographic analysis of the saccharide-binding domain of p75/AIRM1
Siglec-7 and Siglec-9 are capable of negative regulation of TCR signaling and ligand binding is required for optimal activity
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
sialic acid binding Ig-like lectin 7
, QA79 membrane protein
, adhesion inhibitory receptor molecule 1, siglec-7
, sialic acid binding immunoglobulin-like lectin 7
, sialic acid-binding Ig-like lectin 7