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Sialidase 4 Proteins (NEU4)

The protein encoded by NEU4 belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Additionally we are shipping Sialidase 4 Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEU4 129807 Q8WWR8
NEU4 241159 Q8BZL1
Rat NEU4 NEU4 316642  
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Top Sialidase 4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NEU4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Sialidase 4 (NEU4) Interaction Partners

Human Sialidase 4 (NEU4) interaction partners

  1. The silencing or chemical inhibition of NEU4 changes the entire glycosylation pattern of proteins and lipids, making it more similar to that of differentiated GBM cells and drastically reduces GSCs survival.

  2. The results demonstrate that the proline-rich region can also enhance cell proliferation and retinoic acid (RA)-induced neuronal differentiation and it is also involved in NEU4 interaction with Akt (show AKT1 Proteins).

  3. Overexpression of NEU4 is associated with neuroblastoma (show ARHGEF16 Proteins).

  4. NEU4 is involved in regulation of neuronal function by polySia degradation in mammals.

  5. NEU4 plays an important role in control of sialyl Lewis antigen expression and its impairment in colon cancer

  6. The NEU4 long form localizes in mitochondria, while the short form is also associated with the endoplasmic reticulum.

  7. The NEU4 gene, identified by searching sequence databases for entries showing homologies to the human cytosolic sialidase NEU2 (show NEU2 Proteins), maps in 2q37 and encodes a 484-residue protein.

  8. Neu4 is a novel human lysosomal lumen sialidase

  9. Data show that the differentiation of monocytes into macrophages is associated with regulation of the expression of at least three distinct cellular sialidases, Neu1 (show NEU1 Proteins), 3, and 4, with specific up-regulation of the enzyme activity of only Neu1 (show NEU1 Proteins).

Mouse (Murine) Sialidase 4 (NEU4) interaction partners

  1. NEU4 is involved in regulation of neuronal function by polySia degradation in mammals.

  2. Neu4 is not the only sialidase contributing to the metabolic bypass in Hexa (show HEXA Proteins)(-/-) mice.

  3. Neu4 is a functional component of the ganglioside-metabolizing system, contributing to the postnatal development of the brain and other vital organs.

  4. mouse Neu4 plays an important regulatory role in neurite formation, possibly through desialylation of glycoproteins

Sialidase 4 (NEU4) Protein Profile

Protein Summary

The protein encoded by this gene belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with Sialidase 4 Proteins (NEU4)

  • sialidase 4 (NEU4)
  • sialidase 4 (Neu4)
  • 9330166I04 protein

Protein level used designations for Sialidase 4 Proteins (NEU4)

N-acetyl-alpha-neuraminidase 4 , neuraminidase 4 , sialidase-4

GENE ID SPECIES
129807 Homo sapiens
241159 Mus musculus
316642 Rattus norvegicus
609668 Canis lupus familiaris
528030 Bos taurus
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