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SCUBE1 encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Additionally we are shipping SCUBE1 Kits (11) and SCUBE1 Proteins (3) and many more products for this protein.
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The results of this pioneering study indicate that SCUBE protein family appears to have a probable role in the pathogenesis and angiogenesis development in psoriasis and SCUBE 1 and 3 may be novel markers of angiogenesis in psoriasis.
enhanced SCUBE1 concentrations are correlated with increasing severity and poor outcomes of aneurysmal subarachnoid hemorrhage patients, indicating SCUBE1 might have the potential to identify aneurysmal subarachnoid hemorrhage patients at risk of poor prognosis
Increased serum SCUBE1 concentrations have close relation to increasing severity and poor prognosis of intracerebral hemorrhage
SCUBE1 might be a novel prognostic biomarker after traumatic brain injury
SCUBE1 may indicate hypercoagulability in patients with BC and thus help identify patients at greater risk of thrombosisSCUBE1 may indicate hypercoagulability in patients with breast cancer and thus help identify patients at greater risk of thrombosis
SCUBE1 levels are a new biomarker that can be used in the differential diagnosis and monitoring of patients hospitalized with suspected CCHF.
Primary prostatic cancer-associated fibroblasts (CAFs (show TBX1 Antibodies)) were isolated and the expression of CAF (show KAT2B Antibodies) markers, Dlk1 (show DLK1 Antibodies) and SCUBE1 transcripts were characterised.
SCUBE 1 levels in patients with gastric cancer were found higher compared to healthy subjects.
SCUBE1 level, a potential acute ischemia marker, is elevated in hemodialysis patients with no clinical ischemic event.
SCUBE1 participates in platelet aggregation by bridging adjacent activated platelets in thrombosis. Blockade of soluble SCUBE1 might represent a novel antithrombotic strategy.
SCUBE1 may be involved in the regulation of tubular cell proliferation and re-epithelialization during the resolution of kidney injury.
These results support the dual roles of SCUBE1 on brain morphogenesis and cell-cell adhesions through its distinct domain function.
During tooth development, Scube1 localized to the dental papilla of both incisor and molar teeth, suggestina a role for Scube1 during early craniofacial development.
This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology.
signal peptide, CUB and EGF-like domain-containing protein 1
, signal peptide-CUB domain-EGF-related 1