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STAT3 Proteins

(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
STAT3 Protein (AA 1-769) (GST tag) STAT3 Protein (AA 1-769) (GST tag) STAT3 Protein (AA 1-769) (GST tag) (ABIN1321594)

STAT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

STAT3 Protein (AA 1-177) (His tag) STAT3 Protein (AA 1-177) (His tag) STAT3 Protein (AA 1-177) (His tag) (ABIN7125094)

STAT3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

STAT3 Protein (AA 670-769) (GST tag) STAT3 Protein (AA 670-769) (GST tag) STAT3 Protein (AA 670-769) (GST tag) (ABIN1321596)

STAT3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

STAT3 Proteins by Grade

Find STAT3 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

STAT3 Proteins by Origin

Find STAT3 Proteins for a variety of species such as anti-Human STAT3, anti-Rat STAT3, anti-Cow STAT3. The species listed below are among those available. Click on a link to go to the corresponding products.

STAT3 Proteins by Source

Here you will find STAT3 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

STAT3 Proteins by Protein Type

Here you can find STAT3 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

STAT3 Proteins by Application

Find STAT3 Proteins validated for a specific application such as WB, SDS, PC, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular STAT3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1321594
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125094
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321596
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095675
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134025
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417759
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417750
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417756
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417762
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417753
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692021
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319035
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401365
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417423
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710422
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our STAT3 Proteins

Qian, Chai, Liang, Wang, Zhou, Xu, Zhang, Zhang, Si, Huang, Huang, Hong, Wang: "KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer." in: Molecular cancer, Vol. 13, pp. 176, (2014) (PubMed).

Leung, Liu, Lin, Lu, Zhong, Susanti, Rao, Wang, Che, Chan, Leung, Chan, Ma: "Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening." in: Methods (San Diego, Calif.), Vol. 71, pp. 38-43, (2014) (PubMed).

Aliases for STAT3 Proteins

signal transducer and activator of transcription 3 (STAT3) Proteins
signal transduction and activation of transcription 3 (stat3) Proteins
signal transducer and activator of transcription 3 (stat3) Proteins
signal transducer and activator of transcription 3 (Stat3) Proteins
signal transducer and activator of transcription 3, gene 1 L homeolog (stat3.1.L) Proteins
signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) Proteins
1110034C02Rik Proteins
Aprf Proteins
APRF Proteins
aprf Proteins
AW109958 Proteins
HIES Proteins
hies Proteins
stat3 Proteins
wu:fc15d02 Proteins
wu:fl59g06 Proteins
Xstat3 Proteins
z-Stat3 Proteins
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