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The protein encoded by STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. Additionally we are shipping Signal Transducing Adaptor Family Member 1 Proteins (10) and many more products for this protein.
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Human Polyclonal STAP1 Primary Antibody for EIA, IHC (p) - ABIN356991
Ma, Dempsey, Stamatiou, Marshall, Liew: Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. in Atherosclerosis 2007
Show all 4 references for ABIN356991
Human Polyclonal STAP1 Primary Antibody for IHC (p), WB - ABIN388275
Minoguchi, Minoguchi, Aki, Joo, Yamamoto, Yumioka, Matsuda, Yoshimura: STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif. in The Journal of biological chemistry 2003
Mutations in STAP1 (show UXT Antibodies) are associated with autosomal dominant hypercholesterolemia.
Taken together, this study implicates a previously unknown role of STAP-1 in pro-inflammatory microglia activation potentially contributing to neuronal apoptosis and degeneration.
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
BCR downstream signaling 1
, signal transducing adaptor family member 1
, signal-transducing adaptor protein 1
, BCR downstream-signaling protein 1
, docking protein BRDG1
, signal-transducing adaptor protein-1
, stem cell adaptor protein 1
, stem cell adaptor protein STAP-1