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anti-Signal Transducing Adaptor Family Member 2 (STAP2) Antibodies

STAP2 encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. Additionally we are shipping Signal Transducing Adaptor Family Member 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STAP2 55620 Q9UGK3
STAP2 106766 Q8R0L1
STAP2 363334  
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Top anti-Signal Transducing Adaptor Family Member 2 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated EIA, WB AP23706PU-N STAP2 antibody staining of Human Breast lysate at 0.3 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Formalin fixed and paraffin embedded human brain tissue stained with STAP2 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of STAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis in MDA-MB231 cell line lysates (35 µg/lane) using STAP2 Antibody (Center) Cat.-No AP54064PU-N. This demonstrates the STAP2 antibody detected the STAP2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184610 (0.03µg/ml) staining of human heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB STAP2 Antibody (Center) (ABIN656667) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of STAP2 expression in HCT116 (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HCT116, using STAP2, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

STAP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Signal Transducing Adaptor Family Member 2 Antibodies

  1. Human Polyclonal STAP2 Primary Antibody for EIA, WB - ABIN954969 : Sekine, Yamamoto, Ikeda, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 5 references for ABIN954969

  2. Human Polyclonal STAP2 Primary Antibody for IHC, ELISA - ABIN184610 : Minoguchi, Minoguchi, Aki, Joo, Yamamoto, Yumioka, Matsuda, Yoshimura: STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN184610

  3. Human Polyclonal STAP2 Primary Antibody for EIA, IHC (p) - ABIN374097 : Ikeda, Miyasaka, Sekine, Mizushima, Muromoto, Nanbo, Yoshimura, Matsuda: STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 4 references for ABIN374097

  4. Human Polyclonal STAP2 Primary Antibody for EIA, WB - ABIN615925 : Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

More Antibodies against Signal Transducing Adaptor Family Member 2 Interaction Partners

Human Signal Transducing Adaptor Family Member 2 (STAP2) interaction partners

  1. STAP2 is upregulated in uterosacral ligaments in pelvic organ prolapse

  2. Our results demonstrate a critical contribution of STAP-2 in BCR-ABL (show ABL1 Antibodies) activity.

  3. STAP-2 is a novel participant in the regulation of T cell apoptosis after stimulation

  4. Interactions of STAP-2 with Brk (show PTK6 Antibodies) and STAT3 (show STAT3 Antibodies) participate in cell growth of human breast cancer cells.

  5. STAP-2 expression in Jurkat T cells affects migration following stromal cell-derived factor-1alpha (SDF-1alpha) treatment; STAP-2 association with Vav1, the guanine-nucleotide exchanging factor for Rac1, enhances downstream Vav1/Rac1 signaling.

  6. These data indicate that STAP-2/BKS negatively controls the FcepsilonRI (show FCER1G Antibodies)-mediated calcium mobilization and degranulation by direct modulation of tyrosine phosphorylation of PLC (show HSPG2 Antibodies)-gamma.

  7. STAP-2/BKS is a modulator of STAT5 (show STAT5A Antibodies)-mediated signaling

  8. STAP-2 associates with FAK (show PTK2 Antibodies) and enhances its degradation, proteasome inhibitors block FAK (show PTK2 Antibodies) degradation, and STAP-2 recruits an endogenous E3 ubiquitin ligase (show MUL1 Antibodies), Cbl (show CBL Antibodies), to FAK (show PTK2 Antibodies).

  9. These results suggest that STAP-2 acts as an endogenous negative regulator of Epstein-Barr virus LMP1 (show PDLIM7 Antibodies)-mediated signaling through TRAF3 (show TRAF3 Antibodies) and TRADD (show TRADD Antibodies).

  10. STAP-2 is phosphorylated at Tyr250 by Brk (show PTK6 Antibodies), and plays an important role in Brk (show PTK6 Antibodies)-mediated STAT3 (show STAT3 Antibodies) activation.

Mouse (Murine) Signal Transducing Adaptor Family Member 2 (STAP2) interaction partners

  1. results demonstrate a contribution of CCR7 (show CCR7 Antibodies) to STAP-2-dependent enhancement of BCR-ABL (show ABL1 Antibodies)-mediated cell growth in Ba/F3 cells

  2. signal transducing adaptor protein 2 (STAP-2) is involved in cell migration, proliferation, and melanogenesis as well as chemokine receptor (show CCR1 Antibodies) expression and tumorigenesis in B16F10 melanoma cells

  3. STAP-2 has a potential to regulate plural molecular events during pathological inflammatory responses.

  4. Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses.

  5. Our results demonstrate a critical contribution of STAP-2 in BCR-ABL (show ABL1 Antibodies) activity.

  6. STAP-2 is a novel participant in the regulation of T cell apoptosis after stimulation

  7. STAP-2/BKS is a modulator of STAT5 (show STAT5A Antibodies)-mediated signaling

  8. STAP-2 directly binds to c-Fms (show CSF1R Antibodies) and interferes with the PI3K signaling, which leads to macrophage motility, in Raw 264.7 cells

  9. STAP-2 associates with FAK (show PTK2 Antibodies) and enhances its degradation, proteasome inhibitors block FAK (show PTK2 Antibodies) degradation, and STAP-2 recruits an endogenous E3 ubiquitin ligase (show MUL1 Antibodies), Cbl (show CBL Antibodies), to FAK (show PTK2 Antibodies).

  10. These results suggest that STAP-2 acts as an endogenous negative regulator of Epstein-Barr virus LMP1 (show PDLIM7 Antibodies)-mediated signaling through TRAF3 (show TRAF3 Antibodies) and TRADD (show TRADD Antibodies).

Signal Transducing Adaptor Family Member 2 (STAP2) Antigen Profile

Protein Summary

This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with STAP2

  • signal transducing adaptor family member 2 (STAP2) antibody
  • signal transducing adaptor family member 2 (Stap2) antibody
  • AW049765 antibody
  • BKS antibody
  • STAP-2 antibody

Protein level used designations for STAP2

signal-transducing adaptor protein 2 , BRK substrate , breast tumor kinase substrate , brk kinase substrate , signal-transducing adaptor protein-2

GENE ID SPECIES
505456 Bos taurus
55620 Homo sapiens
106766 Mus musculus
363334 Rattus norvegicus
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