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anti-Signal-Induced Proliferation-Associated 1 (SIPA1) Antibodies

The product of SIPA1 is a mitogen induced GTPase activating protein (GAP). Additionally we are shipping SIPA1 Kits (3) and SIPA1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIPA1 20469  
SIPA1 6494 Q96FS4
SIPA1 361710  
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Top anti-SIPA1 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SIPA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate WB Suggested Anti-SIPA1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185175 staining (1µg/ml) of Human EBV-immortilized lymphoblastoid lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 ug/mL. Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 μg/mL. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Hamster Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed mouse ESC, using SIPA1, antibody at 1:200 dilution. IHC-P Image SIPA1 antibody [C3], C-term detects SIPA1 protein at weak membrane and cytosol on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. SIPA1 antibody [C3], C-term , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB SIPA1 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SIPA1 antibody detected the SIPA1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

SIPA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SIPA1 Antibodies

  1. Hamster Monoclonal SIPA1 Primary Antibody for IP, WB - ABIN1449260 : Weissmann: Molecular genetics of transmissible spongiform encephalopathies. in The Journal of biological chemistry 1999 (PubMed)
    Show all 7 references for ABIN1449260

  2. Human Monoclonal SIPA1 Primary Antibody for IP, WB - ABIN1449259 : Kometani, Aoki, Kawamata, Shinozuka, Era, Taniwaki, Hattori, Minato: Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model. in Cancer research 2006 (PubMed)
    Show all 7 references for ABIN1449259

  3. Human Polyclonal SIPA1 Primary Antibody for EIA, IF - ABIN1450109 : Hattori, Tsukamoto, Nur-e-Kamal, Rubinfeld, Iwai, Kubota, Maruta, Minato: Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression. in Molecular and cellular biology 1995 (PubMed)
    Show all 4 references for ABIN1450109

  4. Human Polyclonal SIPA1 Primary Antibody for EIA, IHC (p) - ABIN401404 : Kurachi, Wada, Tsukamoto, Maeda, Kubota, Hattori, Iwai, Minato: Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product. in The Journal of biological chemistry 1997 (PubMed)

  5. Human Polyclonal SIPA1 Primary Antibody for WB - ABIN2787827 : Lee, Nah, Hong, Lee, Jeon, Pak, Huh, Kim, Chae, Kang, Kim, Kim: Spa-1 regulates the maintenance and differentiation of human embryonic stem cells. in The International journal of developmental biology 2007 (PubMed)

More Antibodies against SIPA1 Interaction Partners

Mouse (Murine) Signal-Induced Proliferation-Associated 1 (SIPA1) interaction partners

  1. Sipa1 polymorphism is one of the genetic polymorphisms underlying the metastasis efficiency locus Mtes1.

  2. The binding of Bcr/Abl to Spa-1 may cause aberrant subcellular location of Spa-1 and affect migration of these cells.

  3. afadin (show MLLT4 Antibodies) regulates the cyclical activation and inactivation of Rap1 (show TERF2IP Antibodies), Rac1, and RhoA (show RHOA Antibodies) through SPA-1 and ARAP1 (show ARAP1 Antibodies).

Human Signal-Induced Proliferation-Associated 1 (SIPA1) interaction partners

  1. Our results indicate, for the first time, that the SIPA1 -313A>G may have a prognostic role in unresected NSCLC making it a potential predictor of poor survival due to earlier progression.

  2. nuclear SIPA1 contributes to breast cancer cell invasion through the regulation of integrin beta1 signaling.

  3. BRD4 (show BRD4 Antibodies) short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane.

  4. SIPA1 SNPs, rs746429 and rs2306364, were associated with decreased risk of triple-negative breast tumors.

  5. Polymorphism in Sipa1 promoter gene is associated with lung cancer.

  6. Patients with metastatic breast cancer with SIPA1 545 T/T genotype had a significantly worse overall survival than did patients with C/T or C/C genotype (50.0% vs. 62.9%, P = 0.042).

  7. SIPA1 expression is increased in human colorectal cancer.

  8. In this case-control study, SNPs in SIPA1 varied statistically in cervical cancer patients with and without nodal metastases and in MMP9 (show MMP9 Antibodies) after controlling for stage and lymphvascular space invasion.

  9. Data identif a Rap (show LRPAP1 Antibodies) GTPase-activating protein (show RASA1 Antibodies), signal-induced proliferation-associated protein 1 (SPA-1), as a factor that interacts with Brd4 (show BRD4 Antibodies).

  10. SIPA1 germline polymorphisms are associated with aggressive disease behavior in breast cancer.

SIPA1 Antigen Profile

Protein Summary

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Gene names and symbols associated with SIPA1

  • signal-induced proliferation-associated 1 (SIPA1) antibody
  • Signal peptidase I (leader peptidase I) (sipA1) antibody
  • signal-induced proliferation associated gene 1 (Sipa1) antibody
  • signal-induced proliferation-associated 1 (Sipa1) antibody
  • SPA1 antibody

Protein level used designations for SIPA1

signal-induced proliferation-associated gene 1 , Signal peptidase I (leader peptidase I) , signal-induced proliferation-associated 1 , signal-induced proliferation-associated protein 1-like , GTPase-activating protein Spa-1 , signal-induced proliferation-associated protein 1 , sipa-1 , p130 SPA-1

GENE ID SPECIES
715958 Macaca mulatta
3778279 Lactobacillus sakei subsp. sakei 23K
100385492 Callithrix jacchus
100579653 Nomascus leucogenys
20469 Mus musculus
6494 Homo sapiens
361710 Rattus norvegicus
483730 Canis lupus familiaris
100517325 Sus scrofa
508234 Bos taurus
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