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anti-Single-Stranded DNA Binding Protein 1, Mitochondrial (SSBP1) Antibodies

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). Additionally we are shipping SSBP1 Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SSBP1 381760 Q9CYR0
SSBP1 6742 Q04837
SSBP1 54304 P28042
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Top anti-SSBP1 Antibodies at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HuvEc/HeLa cells, using MtSSB Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using MtSSB Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: SSBP1  Sample Tissue: Human Fetal Heart  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SSBP1 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (42.02 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of SSBP1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of SSBP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$412.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SSBP1 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SSBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,
,

Human , , ,
, ,
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Rat (Rattus) ,
,

Top referenced anti-SSBP1 Antibodies

  1. Human Polyclonal SSBP1 Primary Antibody for IF, IHC - ABIN1533835 : Tiranti, Rocchi, DiDonato, Zeviani: Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB). in Gene 1993 (PubMed)
    Show all 2 references for ABIN1533835

  2. Human Monoclonal SSBP1 Primary Antibody for ELISA, WB - ABIN520501 : Gonçalves, Máximo, Lima, Singh, Soares, Videira: Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. in Biochimica et biophysica acta 2011 (PubMed)

More Antibodies against SSBP1 Interaction Partners

Mouse (Murine) Single-Stranded DNA Binding Protein 1, Mitochondrial (SSBP1) interaction partners

  1. SSBp1 deletion results in increased chromosomal aberrations and localizes to telomeres and participate in the repair of uncapped telomeres.

  2. overexpression of Mitogenin I (show POLDIP2 Antibodies) or mitochondrial single-stranded DNA-binding protein (show RPA1 Antibodies) increased elongated or fragmented mitochondria in mouse C2C12 myoblast cells, respectively.

Human Single-Stranded DNA Binding Protein 1, Mitochondrial (SSBP1) interaction partners

  1. The stimulatory effect of mtSSB on Pol gamma (show POLG Antibodies) on these ssDNA templates is not species-specific.

  2. This study determined that hSSB1 acetylation at K94 mediated by the acetyltransferase p300 and the deacetylases SIRT4 and HDAC10 impaired its ubiquitin-mediated degradation by proteasomes.

  3. SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 (show HSF1 Antibodies) transcriptional activity

  4. Fbxl5 (show FBXL5 Antibodies) interacts with and targets hSSB1 for ubiquitination and degradation, which could be prevented by ATM (show ATM Antibodies)-mediated hSSB1 T117 phosphorylation.

  5. In response to the DNA damage response, INTS3 (show INTS3 Antibodies)-hSSB1-INTS6 (show INTS6 Antibodies) complex relocates to the DNA damage sites.

  6. Results indicate that hSSB1 may regulate DNA damage checkpoints by positively modulating p53 (show TP53 Antibodies) and its downstream target p21 (show CDKN1A Antibodies).

  7. mtSSB potentially prevents formation of DNA breaks in ssDNA, ensuring that base removal primarily occurs in dsDNA.

  8. Local enrichment of UNG1 (show UNG Antibodies) at DNA-bound mtSSB may furthermore facilitate rapid access to- and processing of the damage once the dsDNA conformation is restored.

  9. mtSSB uses distinct structural elements to interact functionally with its mtDNA replisome partners and to promote proper mtDNA replication in animal cells

  10. hSSB1 may positively modulate p21 (show CDKN1A Antibodies) to regulate cell cycle progression and DNA damage response, implicating hSSB1 as a novel, promising therapeutic target for cancers such as hepatocellular carcinoma

SSBP1 Antigen Profile

Protein Summary

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995

Gene names and symbols associated with SSBP1

  • single-stranded DNA binding protein 1 (Ssbp1) antibody
  • single-stranded DNA binding protein 1 (SSBP1) antibody
  • single-stranded DNA binding protein 1, mitochondrial (SSBP1) antibody
  • single-stranded DNA binding protein 1, mitochondrial (Ssbp1) antibody
  • Sjogren syndrome antigen B (autoantigen La) (SSB) antibody
  • 2810480P10Rik antibody
  • G630031O20Rik antibody
  • Mt-SSB antibody
  • mtDBP antibody
  • mtSSB antibody
  • SOSS-B1 antibody
  • Ssbp antibody
  • Ssbp1 antibody

Protein level used designations for SSBP1

mt-SSB , single-stranded DNA-binding protein, mitochondrial , mtSSB , PWP1-interacting protein 17 , single strand DNA-binding protein P16 , single-stranded DNA binding

GENE ID SPECIES
381760 Mus musculus
515765 Bos taurus
6742 Homo sapiens
54304 Rattus norvegicus
100008866 Oryctolagus cuniculus
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