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Single-Stranded DNA Binding Protein 1 (SSBP1) ELISA Kits

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008].. Additionally we are shipping SSBP1 Antibodies (33) and SSBP1 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SSBP1 SSBP1 79035 Q9BQ15
Anti-Rat SSBP1 SSBP1 362813 Q3SWT1
Anti-Mouse SSBP1 SSBP1 69917 Q8R2Y9
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More ELISA Kits for SSBP1 Interaction Partners

Human Single-Stranded DNA Binding Protein 1 (SSBP1) interaction partners

  1. In the absence of hSSB1, human 8-oxoguanine glycosylase 1 does not localize to chromatin, resulting in the accumulation of 8-oxoguanine in the genome.

  2. The findings demonstrate the importance of hSSB1 in maintaining and repairing DNA replication forks and for overall genomic stability.

  3. Identification of EEf1E1 and OBFC2B as novel BRCA1-partner genes in the DNA double-strand break repair pathway.

  4. SOSS complexes, containing SSB1, do not localize with Replication Protein A (RPA (show RPA1 ELISA Kits)) to replication sites in human cells, yet have a strong effect on double-strand break resection and homologous recombination.

  5. Cells deficient in hSSB1 exhibit increased radiosensitivity, defective checkpoint activation and enhanced genomic instability coupled with a diminished capacity for DNA repair.

  6. hSSB1 and hSSB2 (show OBFC2A ELISA Kits) form two separate complexes with similar structures, and both complexes participate in DNA damage response.

  7. INTS3 (show INTS3 ELISA Kits) controls the SSB1-mediated DNA damage response.

Mouse (Murine) Single-Stranded DNA Binding Protein 1 (SSBP1) interaction partners

  1. SSBp1 deletion results in increased chromosomal aberrations and localizes to telomeres and participate in the repair of uncapped telomeres.

  2. Obfc2b deficiency does not affect initiation of DNA damage checkpoints, Atm (show ATM ELISA Kits) activation, or the maintenance of genomic stability in B lymphocytes & primary fibroblasts. Its role in embryogenesis limited to cell types contributing to bone formation.

  3. overexpression of Mitogenin I (show POLDIP2 ELISA Kits) or mitochondrial single-stranded DNA-binding protein (show RPA1 ELISA Kits) increased elongated or fragmented mitochondria in mouse C2C12 myoblast cells, respectively.

SSBP1 Antigen Profile

Antigen Summary

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008

Gene names and symbols associated with SSBP1

  • single-stranded DNA binding protein 1, mitochondrial (SSBP1) antibody
  • single-stranded DNA binding protein 1 (SSBP1) antibody
  • single-stranded DNA binding protein 1, mitochondrial (ssbp1) antibody
  • nucleic acid binding protein 2 (NABP2) antibody
  • nucleic acid binding protein 2 (Nabp2) antibody
  • nucleic acid binding protein 2 (nabp2) antibody
  • oligonucleotide/oligosaccharide-binding fold containing 2B (NABP2) antibody
  • single-stranded DNA binding protein 1 (Ssbp1) antibody
  • single-stranded DNA binding protein 1 (LOC100357130) antibody
  • 2610036N15Rik antibody
  • 2810480P10Rik antibody
  • G630031O20Rik antibody
  • hSSB1 antibody
  • Mt-SSB antibody
  • mtDBP antibody
  • MtSSB antibody
  • nabp2-a antibody
  • Obfc2b antibody
  • obfc2b-a antibody
  • RGD1308158 antibody
  • SOSS-B1 antibody
  • ssb1 antibody
  • ssbp antibody
  • SSBP1 antibody

Protein level used designations for SSBP1

single-stranded DNA-binding protein, mitochondrial , single-stranded DNA binding protein 1 , LP3587 , SOSS complex subunit B1 , nucleic acid-binding protein 2 , oligonucleotide/oligosaccharide-binding fold containing 2B , oligonucleotide/oligosaccharide-binding fold-containing protein 2B , sensor of single-strand DNA complex subunit B1 , sensor of ssDNA subunit B1 , single strand DNA-binding protein 1 , single-stranded DNA-binding protein 1 , SOSS-B1 , Oligonucleotide/oligosaccharide-binding fold containing 2B-A , SOSS complex subunit B1-A , SOSS-B1-A , nucleic acid-binding protein 2-A , oligonucleotide/oligosaccharide-binding fold-containing protein 2B-A , sensor of single-strand DNA complex subunit B1-A , sensor of ssDNA subunit B1-A , single-stranded DNA-binding protein 1-A , mt-SSB , mtSSB

GENE ID SPECIES
418122 Gallus gallus
694459 Macaca mulatta
741448 Pan troglodytes
780115 Xenopus (Silurana) tropicalis
100174293 Pongo abelii
79035 Homo sapiens
362813 Rattus norvegicus
69917 Mus musculus
446552 Xenopus laevis
533842 Bos taurus
381760 Mus musculus
515765 Bos taurus
100357130 Oryctolagus cuniculus
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