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SSBP2 is a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010].. Additionally we are shipping Single-Stranded DNA Binding Protein 2 Antibodies (45) and Single-Stranded DNA Binding Protein 2 Kits (3) and many more products for this protein.
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The minor allele of SSBP2 SNP rs17296479 and the increased tumor expression of SSBP2 were statistically significantly associated with poorer overall survival among glioblastoma patients
results indicate that cigarette smoking is a cause of SSBP2 promoter methylation and that SSBP2 harbors a tumor suppressive role in ESCC through inhibition of the Wnt (show WNT2 Proteins) signaling pathway
Our findings are consistent with human SSBP2 being a novel regulator of hematopoietic growth and differentiation, whose loss confers a block in differentiation advantage to myeloid leukemic cells.
Results suggest that subverting SSBP2 function by oncoprotein E1B55K may contribute to cell transformation by viral oncoproteins.
SSBP2 inhibits prostate cancer cell proliferation and seems to represent a novel prostate cancer-specific DNA marker, especially in high stages of human prostate cancer.
SSBP2-JAK2 (show JAK2 Proteins) fusion gene resulting from a t(5;9)(q14.1;p24.1) is associated with pre-B acute lymphocytic leukemia.
ZNF198-FGFR1 (show FGFR1 Proteins) is associated with phosphorylation of several proteins including SSBP2, ABL (show ABL1 Proteins), FLJ14235, CALM and TRIM4 (show TRIM4 Proteins) proteins.
The results uncovered a critical regulatory function for SSBP2 in hematopoietic stem and progenitor cells gene expression and function.
SSbp2 localizes to telomeres and participate in the repair of uncapped telomeres
SSBP2 is a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009)
single-stranded DNA binding protein 2
, sequence-specific single-stranded-DNA-binding protein 2
, single-stranded DNA-binding protein 2