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Sirtuin 7 Proteins (SIRT7)

SIRT7 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 7 Antibodies (158) and Sirtuin 7 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SIRT7 51547 Q9NRC8
SIRT7 209011 Q8BKJ9
SIRT7 303745  
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Top Sirtuin 7 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 5 to 8 Days
$236.25
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
HOST_Baculovirus infected Insect Cells Human His tag   5 μg Log in to see 10 to 12 Days
$365.64
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details

SIRT7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Sirtuin 7 (SIRT7) Interaction Partners

Human Sirtuin 7 (SIRT7) interaction partners

  1. Novel interactions of TPPII (show Tpp2 Proteins), p53 (show TP53 Proteins), and SIRT7 presented in this study might contribute to the knowledge of the regulatory effects of these proteins on apoptotic pathways and to the understanding mechanisms of aging and lifespan regulation.

  2. SIRT7 deacetylates U3-55k (show RRP9 Proteins), enhancing U3-55k (show RRP9 Proteins) binding to U3 snoRNA, which is a prerequisite for pre-rRNA processing.

  3. this is the first report on the regulation mechanism of SIRT7 gene, in which, HDAC3 (show HDAC3 Proteins) collaborated with C/EBPalpha (show CEBPA Proteins) to occupy its responding element in the upstream region of SIRT7 gene and repressed its expression in human cells.

  4. SIRT3 (show SIRT3 Proteins) and SIRT7 possess tumour suppressor properties in the context of pancreatic cancer.

  5. Sirt7 expression was implicated with high histological grade and independently predicted poor clinical outcome in patients with breast cancer, suggesting that Sirt7 might play a role in the malignant progression of breast cancer.

  6. SIRT7 might play a role of oncogene (show RAB1A Proteins) in ovarian malignancy. Down-regulation of SIRT7 significantly reduced ovarian cancer cell growth, repressed colony formation and increased cancer cell apoptosis; up-regulation promoted the migration of cancer cells.

  7. Sirt7 is overexpressed in human gastric cancers. Expression of Sirt7 is markedly correlated with tumor size, metastasis, disease stage and prognosis.

  8. SIRT1 (show SIRT1 Proteins) inhibition caused cell death, while SIRT2 (show SIRT2 Proteins) inhibition resulted in cell cycle arrest. In conclusion, we report the overexpression of SIRT2 (show SIRT2 Proteins) and SIRT7 proteins in cervical cancer

  9. SIRT7 expression was reduced in aged hematopoietic stem cells (HSCs), and SIRT7 up-regulation improved the regenerative capacity of aged HSCs.

  10. Interactions of two highly acetylated proteins, nucleophosmin (NPM1 (show NPM1 Proteins)) and nucleolin (show NCL Proteins), with SIRT6 (show SIRT6 Proteins) and SIRT7 were confirmed by co-immunoprecipitation.

Mouse (Murine) Sirtuin 7 (SIRT7) interaction partners

  1. miR (show MLXIP Proteins)-93 inhibits the metabolic target Sirt7, which we identified as a major driver of in vivo adipogenesis via induction of differentiation and maturation of early adipocyte precursors.

  2. The role of SIRT7 has emerged in protein synthesis, chromatin remodelling, cellular survival and lipid metabolism.

  3. SIRT7 stabilizes and activates the GABP alpha (show GABPA Proteins)/GABPbeta complex via deacetylation of GABPbeta1.

  4. SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.

  5. Study identifies SIRT7 as a cofactor of Myc (show MYC Proteins) for transcriptional repression and delineates a druggable regulatory branch of the ER stress response that prevents and reverts fatty liver disease.

  6. Mybbp1a (show MYBBP1A Proteins) is a novel negative regulator of Sirt7.

  7. SirT7 plays a dominant role in the growth inhibition of the P19 cells.

  8. SIRT7 is a positive regulator of Pol I transcription and is required for cell viability in mammals.

  9. Suggest a critical role of Sirt7 in the regulation of stress responses and cell death in the heart. Enhanced p53 (show TP53 Proteins) activation by lack of Sirt7-mediated deacetylation contributes to the heart phenotype of Sirt7 mutant mice.

  10. Using Sirt7 knockout and overexpressing cells we demonstrate an anti-proliferative role of Sirt7. We also show that Sirt7 expression inversely correlates with the tumorigenic potential of several murine cell lines

Sirtuin 7 (SIRT7) Protein Profile

Protein Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Gene names and symbols associated with Sirtuin 7 Proteins (SIRT7)

  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7)
  • novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) (CH211-258L4.6)
  • phosphate cytidylyltransferase 2, ethanolamine (PCYT2)
  • sirtuin 7 (SIRT7)
  • sirtuin 7 (Sirt7)
  • LOC796135 protein
  • SIR2L7 protein
  • SIRT7 protein

Protein level used designations for Sirtuin 7 Proteins (SIRT7)

sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin 7 , novel protein similar to vertebratesirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) (SIRT7) , NAD-dependent deacetylase sirtuin-7 , sirtuin , NAD-dependent protein deacetylase sirtuin-7 , SIR2-like protein 7 , regulatory protein SIR2 homolog 7 , silent mating type information regulation 2, S.cerevisiae, homolog 7 , sir2-related protein type 7 , sirtuin type 7 , NAD-dependent deacetylase sirtuin 7

GENE ID SPECIES
454975 Pan troglodytes
796135 Danio rerio
422093 Gallus gallus
51547 Homo sapiens
209011 Mus musculus
303745 Rattus norvegicus
483371 Canis lupus familiaris
100125965 Sus scrofa
505662 Bos taurus
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