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The protein encoded by SSH1A belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. Additionally we are shipping and and many more products for this protein.
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Results reveal that SSH1L (show SSH1 Antibodies) is upregulated in a subset of PCs and that the SSH1L (show SSH1 Antibodies)/cofilin-1 (show CFL1 Antibodies) signal pathway is associated positively in PC with cell migration.
Authors show that viral penetration-induced calcium release facilitated herpes simplex virus type 1 intracellular trafficking through activating slingshot 1 (SSH), a phosphatase regulating actin filament dynamics.
The association of IRS4 (show IRS4 Antibodies) with SSH1 (show SSH1 Antibodies) contributes to localized activation of cofilin (show CFL1 Antibodies) in membrane protrusions.
Slingshot 1 downregulation in neuronal cells inactivates cofilin (show CFL1 Antibodies) to facilitate HSV-1 replication.
Thus this study provides evidence for a novel role of LIMK1 (show LIMK1 Antibodies) and SSH-1L (show SSH1 Antibodies) in selectively regulating endothelial cell inflammation associated with intravascular coagulation.
Our work provides evidence that supports the positive role of SSH1L (show SSH1 Antibodies) in the mechanism of stem cell differentiation into cardiomyocyte-like cells.
A high expression of SSH-1L (show SSH1 Antibodies) in peripheral eosinophils in acute exacerbations of asthma may play a role in the activation and migration of eosinophils.
EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.
identified Ser (show SIGLEC1 Antibodies) 402 as a new phosphorylation site within the catalytic domain of human slingshot 1 (SSH1 (show SSH1 Antibodies)).
Results show the significance of SSH1L (show SSH1 Antibodies) in estrogen-induced osteoblastogenic differentiation in favor of adipogenic differentiation from hMSCs.
The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
SSH-like protein 1
, protein phosphatase Slingshot homolog 1
, slingshot homolog 1