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Slingshot Homolog 2 (Drosophila) Proteins (SSH2)

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. Additionally we are shipping SSH2 Antibodies (11) and SSH2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SSH2 237860 Q5SW75
SSH2 85464 Q76I76
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Top SSH2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SSH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Slingshot Homolog 2 (Drosophila) (SSH2) Interaction Partners

Mouse (Murine) Slingshot Homolog 2 (Drosophila) (SSH2) interaction partners

  1. A PLCbeta/PI3Kgamma (show PIK3CG Proteins)-GSK3 signaling pathway regulates cofilin (show CFL1 Proteins) phosphatase slingshot2 and neutrophil polarization and chemotaxis.

Human Slingshot Homolog 2 (Drosophila) (SSH2) interaction partners

  1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified.

  2. data indicate that: (a) apoptotic cell death in FLCN (show FLCN Proteins)-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD (show FLCN Proteins) syndrome related tumors

  3. Expression of phosphatase-dead versions of SSH proteins, SSH1 (show SSH1 Proteins), SSH2 & SSH3 (show SSH3 Proteins) results in phosphorylation/inactivation of cofilin (show CFL1 Proteins), changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.

SSH2 Protein Profile

Protein Summary

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1\; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002

Gene names and symbols associated with SSH2

  • slingshot homolog 2 (Drosophila) (Ssh2)
  • slingshot protein phosphatase 2 (SSH2)
  • BB104748 protein
  • BC030940 protein
  • mSSH-2L protein
  • SSH-2 protein
  • SSH-2L protein

Protein level used designations for SSH2

SSH-2L , SSH-like protein 2 , protein phosphatase Slingshot homolog 2 , slingshot 2L , slingshot-like 2

GENE ID SPECIES
237860 Mus musculus
85464 Homo sapiens
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