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Slit Homolog 1 (Drosophila) Proteins (SLIT1)

homolog of Drosophila slit\; may play a role in protein-protein interactions during midline formation in the central nervous system\; specifically expressed in fetal and adult forebrain neurons [RGD, Feb 2006].. Additionally we are shipping SLIT1 Antibodies (68) and SLIT1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLIT1 20562 Q80TR4
Rat SLIT1 SLIT1 65047 O88279
SLIT1 6585 O75093
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Top SLIT1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_CHO Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$449.63
Details

SLIT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for Slit Homolog 1 (Drosophila) (SLIT1) Interaction Partners

Rhesus Monkey Slit Homolog 1 (Drosophila) (SLIT1) interaction partners

  1. These results suggested that the role of SLIT1 is altered postnatally and that this is particularly important for prefrontal connectivity in the Old World monkey cortex.

Xenopus laevis Slit Homolog 1 (Drosophila) (SLIT1) interaction partners

  1. Slit acts via Robo2 (show ROBO2 Proteins) in dendrites as a branching/growth factor but not in guidance, while Robo2 (show ROBO2 Proteins) and Robo3 (show ROBO3 Proteins) function in concert in axons to mediate axonal interactions and respond to Slits as guidance factors

Mouse (Murine) Slit Homolog 1 (Drosophila) (SLIT1) interaction partners

  1. Data indicate the roles of Slit1/Robo1 (show ROBO1 Proteins) and Netrin1/DCC (show DCC Proteins) signals in positioning motor neuron cell bodies.

  2. a role for Slit1 in corpus callosum development

  3. Robo-2 (show ROBO2 Proteins)-mediated targeting of P2 axons along the dorsoventral axis of the OB is controlled by Slit-1 expression

  4. This study demonistrated that production of IPCs is enhanced in Robo1 (show ROBO1 Proteins)/2 and Slit1/2 mutants, suggesting that Slit/Robo signaling modulates the transition between primary and intermediate progenitors.

  5. Disruption of either the Robo1 (show ROBO1 Proteins) or Slit1 genes accelerates progression of thalamocortical axons in vivo.

  6. Slit1 has a dual context-dependent role in thalamocortical axons formation

  7. Robo1 (show ROBO1 Proteins) and Robo2 (show ROBO2 Proteins) are expressed in the nucleus origin of the tract of the postoptic commissure TPOC (nTPOC), while Slit expression domains flank the TPOC trajectory.

  8. Nkx2.9 controls SACMN axon exit from the mammalian spinal cord by regulating Robo-Slit signaling

  9. Data show that only Nck2 (show NCK2 Proteins) is required for the Slit1-induced changes in cortical neuron morphology in vitro.

  10. These results indicate that Slit1/2 - Robo1 (show ROBO1 Proteins)/2 signaling is critical during the initial establishment of dopaminergic pathways, with roles in the dorsoventral positioning and precise pathfinding of these ascending longitudinal axons.

Human Slit Homolog 1 (Drosophila) (SLIT1) interaction partners

  1. evidence showing that Slit1 and Slit2 proteins are selective inhibitors and repellents for dorsally projecting, but not for ventrally projecting, cranial motor axons

  2. In fetal and embryonic stem cell cultures Slit-1 inhibited neurite outgrowth.

  3. Slits are negative regulators of Sdf1 (show CXCL12 Proteins) and Cxcr4 (show CXCR4 Proteins) in breast cancer cells.

SLIT1 Protein Profile

Protein Summary

homolog of Drosophila slit\; may play a role in protein-protein interactions during midline formation in the central nervous system\; specifically expressed in fetal and adult forebrain neurons

Gene names and symbols associated with SLIT1

  • slit homolog 1 (Drosophila) (SLIT1)
  • slit homolog 1 (slit1)
  • slit homolog 1 (SLIT1)
  • slit homolog 1 (Drosophila) (slit1)
  • slit homolog 1 (Drosophila) (Slit1)
  • MEGF4 protein
  • mKIAA0813 protein
  • SLIL1 protein
  • SLIT-1 protein
  • slit1 protein
  • SLIT3 protein

Protein level used designations for SLIT1

slit homolog 1 (Drosophila) , slit homolog 1 , slit homolog 1 protein-like , slit homolog 1 protein , slit-1 , multiple EGF-like domains protein 4 , multiple epidermal growth factor-like domains 4 , multiple epidermal growth factor-like domains protein 4

GENE ID SPECIES
486818 Canis lupus familiaris
595147 Canis lupus familiaris
705901 Macaca mulatta
100036682 Xenopus (Silurana) tropicalis
100406024 Callithrix jacchus
100459557 Pongo abelii
100483249 Ailuropoda melanoleuca
100559877 Anolis carolinensis
100583873 Nomascus leucogenys
100609860 Pan troglodytes
380270 Xenopus laevis
20562 Mus musculus
65047 Rattus norvegicus
395293 Gallus gallus
6585 Homo sapiens
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