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GTPase activating protein that acts on ARF1. Additionally we are shipping SMAP2 Antibodies (30) and SMAP2 Proteins (6) and many more products for this protein.
SMAP2 has an ability to mediate the 2,4-dichlorophenoxyacetic acid response and is expressed only in restricted tissues.
SMAP2 (show BRD8 ELISA Kits) immunoprecipitated clathrin and AP-1 (show FOSB ELISA Kits) through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 (show BRD8 ELISA Kits) mutants that did not interact with clathrin or AP-1 (show FOSB ELISA Kits) could not localize to recycling endosomes
Results also demonstrated a physical association between SMAP1 (show UNC45A ELISA Kits) and SMAP2 (show BRD8 ELISA Kits), which might serve as a basis for a functional interaction, and identified the intramolecular domains responsible for this association
In the current study, there were identified sequences in the carboxy-terminal region of SMAP2 that are critical for its specific subcellular localization and its specificity for Arf proteins.
either SMAP1 (show SMAP1 ELISA Kits) or SMAP2, is required for proper embryogenesis
study reveals a link between SMAP2 and CALM/syntaxin2 in clathrin-coated vesicle formation from the trans-Golgi network and subsequent acrosome formation
the trans-Golgi network (TGN (show TG ELISA Kits)) was verified as an additional site of SMAP2 localization based on its co-localization with various TGN (show TG ELISA Kits)-marker proteins.
GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
stromal membrane-associated GTPase-activating protein 2
, small ArfGAP2
, stromal membrane-associated protein 2