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SGTA encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Additionally we are shipping Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha Proteins (18) and many more products for this protein.
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Human Polyclonal SGTA Primary Antibody for EIA, WB - ABIN954783
Dutta, Tan: Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1. in Biochemistry 2008
Show all 3 references for ABIN954783
the binding of SGTA to Rpn13 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation.
data suggest that SGTA regulates the cellular fate of a range of hydrophobic polypeptides should they become exposed to the cytosol.
Data show that molecular chaperone (show HSP90AA1 Antibodies) BAG6_ubiquitin-like domain (UBL) and ubiquitin-like 4A (show UBL4A Antibodies) UBL4A_UBL compete for the same binding site on N-terminal dimerisation domain of SGTA protein (SGTA_NT).
SGTA overexpression may be involved in the pathogenesis of breast cancer which might serve as a future target for novel treatment in breast cancer.
Our data suggest a role for SGTA at distinct steps in the chaperone-dependent modulation of androgen, glucocorticoid, and progesterone receptor (show PGR Antibodies) activity.
SGTA depletion decreased cyclin A (show CCNA2 Antibodies) and cyclin B levels.
A role of SGTA in Non-Hodgkin's lymphoma (NHL (show RTEL1 Antibodies)) cell proliferation, adhesion and drug resistance, and it may pave the way for a novel therapeutic approach for cell adhesion-mediated drug resistance in NHL (show RTEL1 Antibodies).
High expression of SGTA in esophageal squamous cell carcinoma correlates with proliferation and poor prognosis.
Univariate analysis showed that the low SGTB expression was associated with poor prognosis (P<0.001)
High Small glutamine-rich tetratricopeptide repeat-containing protein alpha expression is associated with non-small-cell lung cancer tumorigenesis.
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein\; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
, small glutamine-rich tetratricopeptide
, small glutamine-rich tetratricopeptide repeat-containing protein beta
, small glutamine-rich tetratricopeptide repeat-containing protein alpha
, protein containing three tetratricopeptide repeats
, vpu-binding protein
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein
, small glutamine-rich protein with tetratricopeptide repeats 1
, small glutamine-rich tetratricopeptide repeat (TPR) containing protein (SGT)