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Two types of spliceosomes catalyze splicing of pre-mRNAs. Additionally we are shipping Small Nuclear Ribonucleoprotein 25kDa (U11/U12) Antibodies (4) and many more products for this protein.
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Human SNRNP25 Protein expressed in Escherichia coli (E. coli) - ABIN667912
De Gobbi, Viprakasit, Hughes, Fisher, Buckle, Ayyub, Gibbons, Vernimmen, Yoshinaga, de Jong, Cheng, Rubin, Wood, Bowden, Higgs: A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. in Science (New York, N.Y.) 2006
Show all 2 references for ABIN667912
Two recurrent fusion genes associated with the 12q locus, LRP1 (show LRP1 Proteins)-SNRNP25 and KCNMB4 (show KCNMB4 Proteins)-CCND3 (show CCND3 Proteins), were by RT-PCR, Sanger sequencing and FISH, and were found to be osteosarcoma specific in a validation cohort of 240 other sarcomas.
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome.
U11/U12 small nuclear ribonucleoprotein 25 kDa protein
, U11/U12 snRNP 25 kDa protein
, U11/U12 snRNP 25K
, minus-99 protein