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anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) Antibodies

Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Additionally we are shipping SNRNP70 Proteins (8) and SNRNP70 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNRNP70 20637 Q62376
SNRNP70 361574  
SNRNP70 6625 P08621
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Top anti-SNRNP70 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SNRP70 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SNRP70 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-SNRP70  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate  SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB SNRNP70 Antibody (Center)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SNRNP70 antibody detected the SNRNP70 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

SNRNP70 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human , ,
, ,
,
, , , , ,

Top referenced anti-SNRNP70 Antibodies

  1. Cow (Bovine) Polyclonal SNRNP70 Primary Antibody for WB - ABIN2778829 : Dieker, Cisterna, Monneaux, Decossas, van der Vlag, Biggiogera, Muller: Apoptosis-linked changes in the phosphorylation status and subcellular localization of the spliceosomal autoantigen U1-70K. in Cell death and differentiation 2008 (PubMed)
    Show all 5 references for ABIN2778829

  2. Cow (Bovine) Polyclonal SNRNP70 Primary Antibody for IHC, WB - ABIN2778715 : Zhang, Walker, Tamplin, Rossant, Stanford, Hughes: Zfp206 regulates ES cell gene expression and differentiation. in Nucleic acids research 2006 (PubMed)
    Show all 4 references for ABIN2778715

More Antibodies against SNRNP70 Interaction Partners

Zebrafish Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) interaction partners

  1. These findings provide evidence for a new role of a general small nuclear ribonucleoprotein particle protein, U1C (show SNRPC Antibodies), as a mediator of alternative splicing regulation.

Human Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) interaction partners

  1. The epitopes of U1-70K autoantibodies have been mapped at single-amino acid resolution.

  2. The authors propose that Gemin2 is a versatile hub for ribonucleoprotein exchange that functions broadly in RNA metabolism.

  3. data lead to a model that FUS (show FUS Antibodies) functions in coupling transcription to splicing via mediating an interaction between RNAP II and U1 snRNP (show LSM2 Antibodies)

  4. The selection of 5'-splice site nucleotides by U1 snRNP (show LSM2 Antibodies) is achieved predominantly through basepairing with U1 snRNA whilst U1-C (show SNRPC Antibodies) fine-tunes relative affinities of mismatched 5'-splice sites.

  5. methylation of snRNP70 by SETMAR (show SETMAR Antibodies) regulates constitutive and/or alternative splicing

  6. U1-70K interacts with the SMN (show STMN1 Antibodies) complex and is required for nuclear gem (show GEM Antibodies) integrity.

  7. Data indicate that small nuclear ribonucleoprotein U1-70K in Alzheimer disease (AD) may directly sequester normal soluble forms of U1-70K into insoluble aggregates.

  8. These studies identify U1 snRNP (show LSM2 Antibodies) pathologic changes in brain of early onset genetic forms of Alzheimer's disease

  9. inhibition of U1 snRNP (show LSM2 Antibodies) also leads to regulation of the usage of In3 pA, suggesting that the C/P activity in the cell can be cross-regulated by splicing, leading to coordination between these two processes.

  10. High expression of U1-70K and other U1 small nuclear ribonucleoproteins spliceosome proteins in Alzheimer's disease patients and those with mild cognitive impairment.

SNRNP70 Antigen Profile

Protein Summary

Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.

Gene names and symbols associated with SNRNP70

  • small nuclear ribonucleoprotein 70kDa (U1) (snrnp70) antibody
  • small nuclear ribonucleoprotein 70kDa (U1) (SNRNP70) antibody
  • small nuclear ribonucleoprotein 70 (U1) (snrnp70) antibody
  • small nuclear ribonucleoprotein 70 (U1) (Snrnp70) antibody
  • 70kDa antibody
  • 2700022N21Rik antibody
  • 3200002N22Rik antibody
  • AI325098 antibody
  • R74807 antibody
  • RNPU1Z antibody
  • Rnulp70 antibody
  • RPU1 antibody
  • Snp1 antibody
  • Snrp70 antibody
  • Srnp70 antibody
  • U1-70 antibody
  • U1-70K antibody
  • U1AP antibody
  • U1RNP antibody
  • U170K antibody
  • wu:fc20b04 antibody
  • zgc:136450 antibody

Protein level used designations for SNRNP70

U1 small nuclear ribonucleoprotein 70 kDa , U1 snRNP 70 kDa , U1-70K , small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen) , small nuclear ribonucleoprotein 70kDa (U1) , U1 small nuclear ribonucleoprotein polypeptide A , U1 small ribonucleoprotein 70kd , small nuclear ribonucleoprotein 70kDa , U1 small nuclear ribonucleoprotein 70 kDa polypeptide A

GENE ID SPECIES
493488 Xenopus (Silurana) tropicalis
747202 Pan troglodytes
100595176 Nomascus leucogenys
445398 Danio rerio
20637 Mus musculus
361574 Rattus norvegicus
397946 Xenopus laevis
6625 Homo sapiens
484388 Canis lupus familiaris
535113 Bos taurus
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