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anti-Smg-7 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG7) Antibodies

SMG7 encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. Additionally we are shipping and SMG7 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse SMG7 SMG7 226517 Q5RJH6
SMG7 9887 Q92540
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Top anti-SMG7 Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HeLa/Jurkat/293/HuvEc cells, using SMG7 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using SMG7 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of SMG7 staining in A431 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of SMG7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ICC   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$595.83
Details

SMG7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,


More Antibodies against SMG7 Interaction Partners

Human Smg-7 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG7) interaction partners

  1. Depletion of nonsense-mediated mRNA decay pathway components Upf1 (show UPF1 Antibodies), Smg5 (show SMG5 Antibodies), and Smg7 led to increased levels of viral proteins and and virus release.

  2. The study demonstrates that SMG5 (show SMG5 Antibodies)-SMG7 and SMG6 (show SMG6 Antibodies) exhibit different and non-overlapping modes of UPF1 (show UPF1 Antibodies) recognition, thus pointing at distinguished roles in integrating the complex nonsense-mediated mRNA decay interaction network.

  3. Data show that phosphorylated hUPF1 (show UPF1 Antibodies), the human ortholog of UPF1/SMG-2 (show UPF1 Antibodies), forms a complex with human orthologs of the Caenorhabditis elegans proteins SMG-5 (show SMG5 Antibodies) and SMG-7.

SMG7 Antigen Profile

Protein Summary

This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with SMG7

  • Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7) antibody
  • SMG7 nonsense mediated mRNA decay factor (SMG7) antibody
  • 9430023P16Rik antibody
  • C1orf16 antibody
  • EST1C antibody
  • mKIAA0250 antibody
  • SGA56M antibody

Protein level used designations for SMG7

EST1-like protein C , protein SMG7 , EST1 telomerase component homolog C , breast cancer-associated antigen SGA-56M , ever shorter telomeres 1C , smg-7 homolog, nonsense mediated mRNA decay factor

GENE ID SPECIES
226517 Mus musculus
9887 Homo sapiens
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