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SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008].. Additionally we are shipping SMG5 Antibodies (31) and SMG5 Proteins (3) and many more products for this protein.
This study highlights that miR (show MLXIP ELISA Kits)-433 represses nonsense mediated mRNA decay. The miR (show MLXIP ELISA Kits)-433 targets 3'-UTR (show UTS2R ELISA Kits) of SMG5 and represses the expression of SMG5, whereas nonsense-mediated mRNA decay activity is decreased when SMG5 is decreased.
Depletion of nonsense-mediated mRNA decay pathway components Upf1 (show UPF1 ELISA Kits), Smg5, and Smg7 led to increased levels of viral proteins and and virus release.
The study demonstrates that SMG5-SMG7 and SMG6 (show SMG6 ELISA Kits) exhibit different and non-overlapping modes of UPF1 (show UPF1 ELISA Kits) recognition, thus pointing at distinguished roles in integrating the complex nonsense-mediated mRNA decay interaction network.
Data show that phosphorylated hUPF1 (show UPF1 ELISA Kits), the human ortholog of UPF1/SMG-2 (show UPF1 ELISA Kits), forms a complex with human orthologs of the Caenorhabditis elegans proteins SMG-5 and SMG-7.
HDAC8 (show HDAC8 ELISA Kits) regulation of hEST1B protein stability modulates total telomerase enzymatic activity
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003
SMG5 homolog nonsense mediated mRNA decay factor
, protein SMG5
, EST1-like protein B
, EST1 telomerase component homolog B
, Est1p-like protein B
, LPTS interacting protein
, LPTS-interacting protein
, ever shorter telomeres 1B
, smg-5 homolog, nonsense mediated mRNA decay factor
, Smg-5 homolog, nonsense mediated mRNA decay factor