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Snail Homolog 1 (Drosophila) Proteins (SNAI1)

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. Additionally we are shipping Snail Homolog 1 (Drosophila) Antibodies (138) and Snail Homolog 1 (Drosophila) Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SNAI1 6615 O95863
Rat SNAI1 SNAI1 116490  
SNAI1 20613 Q02085
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Top Snail Homolog 1 (Drosophila) Proteins at

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

SNAI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Snail Homolog 1 (Drosophila) (SNAI1) Interaction Partners

Fruit Fly (Drosophila melanogaster) Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. evidence for mechanosensitivity of cell-cell junctions and implications that myosin-mediated tension can prevent Snail-driven Eepithelial-mesenchymal transitions

  2. Snail can potentiate enhancer activation by collaborating with different activators, providing a new mechanism by which Snail regulates development.

  3. Rapid transcription kinetics and negative autoregulation are responsible for the remarkable homogeneity of snail expression and the coordination of mesoderm invagination.

  4. Study shows that Sna represses transcription of pbl in the mesoderm primordium of D. melanogaster via one or more Sna-binding sites, which are conserved among species of the Drosophila genus, but not in the mosquito, correlating with the different modes of gastrulation in the different genuses.

  5. Complex interactions between cis (show CISH Proteins)-regulatory modules in native conformation are critical for Drosophila snail expression.

  6. The Snail repressor positions Notch (show NOTCH1 Proteins) signaling in the Drosophila embryo.

  7. results show that Sna has a positive regulatory function on sim (show SIM2 Proteins) expression in the presumptive mesectoderm; this positive effect of Sna depends on the Su(H (show RBPJ Proteins))-binding sites within the sim (show SIM2 Proteins) promoter, suggesting that Sna regulates Notch (show NOTCH1 Proteins) signaling

  8. snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu.

  9. Dorsal activates twist and snail, and the Dorsal/Twist/Snail network activates and represses other zygotic genes to form the dorsoventral axis in Drosophila.

  10. Snail represses Tom expression in the mesoderm and thereby activates Delta trafficking.

Xenopus laevis Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. The transcription factor Snail1 is essential for tissue separation, enabling paraxial protocadherin (PAPC (show PCDH8 Proteins)) to promote tissue separation through novel functions.

  2. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

  3. the same E3 ubiquitin ligase (show MUL1 Proteins) known to regulate Snail family proteins, Partner of paired (Ppa (show FBXL14 Proteins)), also controlled Twist stability and did so in a manner dependent on the Twist WR-rich domain

Human Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. Snail and DAB2IP (show DAB2IP Proteins) interact to regulate EMT (show ITK Proteins), invasion and metastasis in colorectal cancer

  2. LASP-1 (show LASP1 Proteins) associated with UHRF1 (show UHRF1 Proteins), G9a (show EHMT2 Proteins), Snail1 and di- and tri (show VANGL2 Proteins)-methylated histoneH3 in a CXCL12 (show CXCL12 Proteins)-dependent manner based on immunoprecipitation and proximity ligation assays

  3. When Notch (show NOTCH1 Proteins)-downstream pathways were analyzed, the study detected an increase in glycogen synthase kinase 3 beta phosphorylation and inactivation that facilitates Snail1 nuclear retention and protein stabilization.

  4. Downregulation of tumor suppressing STF cDNA 3 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by the Wnt (show WNT2 Proteins)/GSK-3beta/beta-catenin (show CTNNB1 Proteins)/Snail signaling pathway.

  5. osthole suppresses the EMT (show ITK Proteins)-mediated metastatic ability in prostate cancer by inhibiting snail signaling and miR (show MLXIP Proteins)-23a-3p

  6. The downregulation of ZEB1, Twist1 (show TWIST1 Proteins), and Snail1 reduces the invasive properties of uveal melanoma cells, and the elevated mRNA levels of ZEB1 and Twist1 (show TWIST1 Proteins) are associated with a more aggressive clinical phenotype in uveal melanoma samples.

  7. the expression levels of HIF1a (show HIF1A Proteins), Snail and Ecadherin were correlated with clinical pathological factors in human ovarian cancer.

  8. ILK (show ILK Proteins) may have an important role in the progression of NSCLC, possibly through up-regulation of Snail and MRP1 (show MDM4 Proteins).

  9. Snail and Slug (show SNAI2 Proteins) expression were up-regulated in the ectotopic endometrium of adenomyosis patients compared with normal endometrium.

  10. DDR2 (show DDR2 Proteins) plays an important role in promoting hepatocellular carcinoma cell invasion and migration by stabilizing SNA1.

Mouse (Murine) Snail Homolog 1 (Drosophila) (SNAI1) interaction partners

  1. miR (show MLXIP Proteins)-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes, such as Smad2 (show SMAD2 Proteins) and Smad5 (show SMAD5 Proteins).

  2. show that Snail1-induced fibrosis can be reversed in vivo and that obstructive nephropathy can be therapeutically ameliorated in mice by targeting Snail1 expression

  3. Results suggest that Snai1 is a key factor that triggers ESCs (show NR2E3 Proteins) exit from the pluripotency state and initiate their differentiation processes.

  4. During embryonic stem cell differentiation, an endogenous Wnt (show WNT2 Proteins)-mediated burst in Snail1 expression regulates neuroectodermal fate while playing a role in epiblast stem cell exit and the consequent lineage fate decisions that define mesoderm commitment.

  5. The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life.

  6. Snail inhibits adipogenesis through a down-regulation of Nr2f6 (show NR2F6 Proteins), which in turn facilitates the expression of IL-17 (show IL17A Proteins), an anti-adipogenic cytokine.

  7. Snail1 acts as a VEGF (show VEGFA Proteins)-induced regulator of Notch1 (show NOTCH1 Proteins) signalling and Dll4 (show DLL4 Proteins) expression. Results document a Snail1-Dll4 (show DLL4 Proteins)/Notch1 (show NOTCH1 Proteins) axis that controls embryonic vascular development.

  8. Cav1 (show CAV1 Proteins) knockout promotes MEK (show MDK Proteins)-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis.

  9. overexpression of Snail in PDAC cells increased SCF (show KITLG Proteins) levels, and the media conditioned by Snail-expressing PDAC cells promoted mast cell migration.

  10. Data indicate an unexpected role for the epithelial-mesenchymal transition factor SNAIL protein in reprogramming somatic cells to pluripotency.

Snail Homolog 1 (Drosophila) (SNAI1) Protein Profile

Protein Summary

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

Gene names and symbols associated with SNAI1

  • snail homolog 1 (Drosophila) (SNAI1)
  • snail 1 homolog (LOC100350709)
  • snail 1 homolog (LOC100352102)
  • snail (sna)
  • zinc-finger transcription factor Snail (snail)
  • snail family zinc finger 1 (snai1)
  • snail protein (Snail)
  • transcription factor protein (snail)
  • snail zinc finger protein (snail)
  • snail family zinc finger 1 (SNAI1)
  • snail family zinc finger 1 (Snai1)
  • snail homolog 1 (Drosophila) (Snai1)
  • AI194338 protein
  • BG:DS01845.1 protein
  • br28 protein
  • br29 protein
  • CG3956 protein
  • dJ710H13.1 protein
  • Dmel\\CG3956 protein
  • l(2)35Db protein
  • l(2)br28 protein
  • l(2)br29 protein
  • l(3)br28 protein
  • l35Db protein
  • Sco protein
  • SLUGH2 protein
  • sn protein
  • sna protein
  • Sna1 protein
  • SNAH protein
  • Snai protein
  • SNAI1 protein
  • Snail protein
  • Snail1 protein
  • xSna protein
  • Xsnail protein

Protein level used designations for SNAI1

snail homolog 1 , snail like protein , Protein snail-like protein 1 , snail homolog 1 (Drosophila) , snail 1 homolog , CG3956-PA , scutoid , sna-PA , zinc-finger transcription factor Snail , protein Xsnail , protein snail homolog Sna , protein xSna , snail protein , zinc finger protein with snail domain similar to escargot , transcription factor protein , snail zinc finger protein , snail-like protein 1 , protein sna , protein snail homolog 1 , snail 1 zinc finger protein , snail 1, zinc finger protein , zinc finger protein SNAI1

396047 Gallus gallus
702353 Macaca mulatta
745644 Pan troglodytes
100127224 Ovis aries
100350709 Oryctolagus cuniculus
100352102 Oryctolagus cuniculus
34908 Drosophila melanogaster
378469 Strongylocentrotus purpuratus
379615 Xenopus laevis
410464 Apis mellifera
778762 Ciona intestinalis
100303552 Saccoglossus kowalevskii
100029017 Monodelphis domestica
6615 Homo sapiens
116490 Rattus norvegicus
20613 Mus musculus
485924 Canis lupus familiaris
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