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anti-Snail Homolog 2 (Drosophila) (SNAI2) Antibodies

SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors.

list all antibodies Gene Name GeneID UniProt
Anti-Human SNAI2 SNAI2 6591 O43623
Anti-Rat SNAI2 SNAI2 25554 O08954
Anti-Mouse SNAI2 SNAI2 20583 P97469
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More Antibodies against Snail Homolog 2 (Drosophila) Interaction Partners

Xenopus laevis Snail Homolog 2 (Drosophila) (SNAI2) interaction partners

  1. Interaction with Snail1 (show SNAI1 Antibodies)/2, and Twist function more generally, is regulated by GSK-3-beta (show GSK3b Antibodies)-mediated phosphorylation of conserved sites in the WR domain.

  2. The Slug controls epithelial-mesenchymal transitions during both embryonic development and tumor metastasis.

  3. These results identify Snail2 as a key regulator of the signals involved in mesodermal induction of neural crest.

  4. A dinucleotide TGTGT/ACACA (show ACACA Antibodies) repeat in the cis (show CISH Antibodies)-element of Snail2 (previously 'Slug') gene contributes to repression of neural crest cell differentiation and migration by all-trans retinoic acid in Xenopus laevis embryos.

Human Snail Homolog 2 (Drosophila) (SNAI2) interaction partners

  1. High SNAI2 expression was significantly correlated with Gastric Cancer.

  2. As a consequence, Slug transcription is down-regulated relieving A549 cells from Slug-mediated repression of E-cadherin transcription, thereby diminishing the metastatic potential of these oncogenic Ras-expressing NSCLC cells

  3. Sox4 was also able to promote b-catenin-mediated transcription of the Slug gene through formation of transcriptional complexes with b-catenin and p300 (show EP300 Antibodies), independent of TCF4 (show TCF4 Antibodies) status

  4. 4-hydroxytamoxifen resistance in breast cancer cells is suppressed by curcumin, which targets the SLUG/Hexokinase 2 (show HK2 Antibodies) pathway

  5. Loss of NDRG2 (show NDRG2 Antibodies) induced the expression of matrix metalloproteinase-19 (MMP-19 (show MMP19 Antibodies)), which regulated the expression of Slug at the transcriptional level in the epithelial-mesenchymal transition of gallbladder carcinoma cells.

  6. we demonstrated that rLZ-8 promoted the interaction between MDM2 (show MDM2 Antibodies) and Slug, resulting in Slug degradation

  7. Our study shows an inversed preferential nuclear expression of SLUG, SOX10 (show SOX10 Antibodies), and SOX9 (show SOX9 Antibodies) in triple negative and non-triple negative cases.

  8. we show that SOX2 (show SOX2 Antibodies) is a transcriptional target of SLUG. These data establish a novel mechanism of breast tumor initiation involving IMP3 (show IGF2BP3 Antibodies) and they provide a rationale for its association with aggressive disease and poor outcome.

  9. SOX2 (show SOX2 Antibodies) Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3 (show STAT3 Antibodies)/HIF-alpha Signaling

  10. It plays an important role in not only invasion ability through EMT but also gemcitabine resistance of CD133-positive pancreatic cancer cells.

Mouse (Murine) Snail Homolog 2 (Drosophila) (SNAI2) interaction partners

  1. TGFbeta3 increases IRF6 (show IRF6 Antibodies) expression and subsequently regulates SNAI2 expression; IRF6 (show IRF6 Antibodies) appears to regulate epithelial mesenchymal transition during palatal fusion via SNAI2.

  2. Our work demonstrates the participation of SNAI2 in the pathogenesis of luminal breast cancer, and reveals an unexpected connection between the processes of postlactational involution and breast tumorigenesis in Snai2-null mutant mice.

  3. SNAI2-driven BIM (show BCL2L11 Antibodies)-induced apoptosis may temper metastasis by governing the survival of disseminating breast tumor cells.

  4. Data indicate that deletion of snail (show SNAI1 Antibodies) family transcription factors Snai2 and Snai3 (show SNAI3 Antibodies) in bone marrow-derived cells is sufficient to induce autoantibody generation.

  5. Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors.

  6. p19(Arf) (p14(ARF (show CDKN2A Antibodies)) in human) stabilizes Slug to inhibit E-cadherin (show CDH1 Antibodies) in prostate cancer mouse models.

  7. SNAIL (show SNAI1 Antibodies) and SLUG probably play important roles during follicular development, luteinization and early embryonic development.

  8. Nanog functions in conjunction with mesenchymal factors Snai1 and Snai2 in the transcriptional regulation of pluripotency-associated genes and miRNAs during the Nanog-driven reprogramming process.

  9. pregnancy-associated mammary stem cells require a TGF-beta2 (show TGFB2 Antibodies)/alphavbeta3/Slug pathway

  10. Slug promotes survival during metastasis through suppression of Puma (show BBC3 Antibodies)-mediated apoptosis.

Zebrafish Snail Homolog 2 (Drosophila) (SNAI2) interaction partners

  1. Snail (show SNAI1 Antibodies) genes lie in regions of extensive paralogy, revealing their common origin through segmental or chromosomal duplication

Snail Homolog 2 (Drosophila) (SNAI2) Antigen Profile

Protein Summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Gene names and symbols associated with SNAI2

  • snail homolog 2 (Drosophila) (SNAI2) antibody
  • snail family zinc finger 2 (snai2) antibody
  • snail family zinc finger 2 (snai2-b) antibody
  • snail family zinc finger 2 (SNAI2) antibody
  • snail family zinc finger 2 (Snai2) antibody
  • snail family zinc finger 2 (snai2-a) antibody
  • snail homolog 2 (Drosophila) (Snai2) antibody
  • snail homolog 2 (Drosophila) (snai2) antibody
  • cb147 antibody
  • cb355 antibody
  • id:ibd5003 antibody
  • sb:cb355 antibody
  • sb:cb569 antibody
  • Slug antibody
  • Slugh antibody
  • SLUGH1 antibody
  • snai2 antibody
  • SNAIL2 antibody
  • WS2D antibody
  • wu:fb83e12 antibody
  • wu:fd19g11 antibody
  • xSlu antibody
  • xslug antibody
  • xsna antibody
  • XSnail2 antibody
  • zgc:92564 antibody

Protein level used designations for SNAI2

snail 2 , Protein snail-like protein 2 , zinc finger protein SNAI2 , snail homolog 2 , zinc finger transcription factor slug , zinc finger transcription factor slug beta , neural crest transcription factor SLUG , protein snail homolog 2 , slug (chicken homolog), zinc finger protein , Slug, chicken homolog , neural crest transcription factor Slug , protein slug-alpha , slug alpha , snail protein homolog Slug , xSlu , slug , zinc finger transcription factor snail 2 , zinc-finger transcription factor SLUG , slug, chicken homolog

GENE ID SPECIES
464169 Pan troglodytes
708962 Macaca mulatta
395065 Xenopus (Silurana) tropicalis
100023459 Monodelphis domestica
398235 Xenopus laevis
6591 Homo sapiens
25554 Rattus norvegicus
379440 Xenopus laevis
432368 Gallus gallus
486940 Canis lupus familiaris
641345 Sus scrofa
520631 Bos taurus
20583 Mus musculus
494038 Danio rerio
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