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anti-Snf2-Related CREBBP Activator Protein (SRCAP) Antibodies

SRCAP encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex.

list all antibodies Gene Name GeneID UniProt
SRCAP 10847 Q6ZRS2
SRCAP 100043597  
SRCAP 361652  
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Top anti-SRCAP Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p), ELISA Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Goat Un-conjugated IHC, ELISA   50 μg Log in to see 11 to 16 Days
$658.43
Details
Human Goat Alkaline Phosphatase (AP) ELISA   100 μL Log in to see 16 Days
$620.71
Details
Human Goat APC ELISA   100 μL Log in to see 16 Days
$620.71
Details
Human Goat Biotin ELISA   100 μL Log in to see 16 Days
$620.71
Details
Human Goat PE ELISA   100 μL Log in to see 16 Days
$620.71
Details
Human Goat FITC ELISA   100 μL Log in to see 16 Days
$620.71
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 11 to 16 Days
$435.29
Details

SRCAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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, , , , ,
Mouse (Murine) , ,
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Rat (Rattus) , ,
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More Antibodies against SRCAP Interaction Partners

Human Snf2-Related CREBBP Activator Protein (SRCAP) interaction partners

  1. Data confirm a mutational hot spot in the final exon of SRCAP in the majority of Floating-Harbor syndrome patients but also show that exon 33 of this gene can be affected.

  2. This study implicates the human SRCAP chromatin remodeling complex as a novel regulator of DNA damage responses that orchestrates proper signaling and repair of DSBs in the context of chromatin.

  3. Functional studies and reports of patients with additional SRCAP mutations will eventually lead to a better understanding of biological mechanisms underlying this disorder.

  4. These results indicate that perturbed skeletal maturation from infancy through adolescence is a characteristic feature in patients with SRCAP mutations.

  5. Sequencing of the SRCAP gene demonstrated a de novo mutation matching one of the known FHS-associated mutations.

  6. Data indicate that the absence of SRCAP mutations in 3/9 cases suggesting genetic heterogeneity of floating-harbor syndrome (FH syndrome).

  7. Our genome-wide expression results demonstrate that SRCAP-mediated H2A.Z (show H2AFZ Antibodies) deposition at promoter regions is necessary for complete gene reactivation induced by DNA demethylation.

  8. Sanger sequencing identified mutations in SRCAP in eight more affected persons.

  9. HCV NS3 protein is involved in the activation of the Notch (show NOTCH1 Antibodies)-signaling pathway through the targeting to both SRCAP and p400 (show EP400 Antibodies)

  10. These data identify SRCAP as a physiologically relevant mediator of PSA (show PLAG1 Antibodies) expression, and demonstrate that SRCAP plays a role in prostate cancer cell proliferation.

SRCAP Antigen Profile

Protein Summary

This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features.

Gene names and symbols associated with SRCAP

  • Snf2-related CREBBP activator protein (SRCAP) antibody
  • Snf2-related CREBBP activator protein (Srcap) antibody
  • B930091H02Rik antibody
  • D030022P06Rik antibody
  • DOMO1 antibody
  • EAF1 antibody
  • F630004O05Rik antibody
  • FLHS antibody
  • RGD1565642 antibody
  • SWR1 antibody

Protein level used designations for SRCAP

Snf2-related CBP activator protein , Swi2/Snf2-related ATPase homolog, domino homolog 1 , domino homolog 2 , helicase SRCAP

GENE ID SPECIES
10847 Homo sapiens
479773 Canis lupus familiaris
100043597 Mus musculus
361652 Rattus norvegicus
100514159 Sus scrofa
788113 Bos taurus
Selected quality suppliers for anti-SRCAP (SRCAP) Antibodies
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