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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. Additionally we are shipping Snurportin 1 Proteins (15) and Snurportin 1 Kits (7) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal SNUPN Primary Antibody for EIA, WB - ABIN954877
Goette, Stumpe, Ficner, Grubmüller: Molecular determinants of snurportin 1 ligand affinity and structural response upon binding. in Biophysical journal 2009
Show all 5 references for ABIN954877
Cow (Bovine) Polyclonal SNUPN Primary Antibody for WB - ABIN2778945
Ospina, Gonsalvez, Bednenko, Darzynkiewicz, Gerace, Matera: Cross-talk between snurportin1 subdomains. in Molecular biology of the cell 2005
analysis of interactions between CRM1 and the nuclear pore protein Tpr and snurportin
SPN (show SPN Antibodies) construct lacking the importin beta (show KPNB1 Antibodies) binding domain (IBB) localizes primarily to the nucleus rather than to the cytoplasm.
There is an interaction between the N- and C-terminal domains of SPN (show SPN Antibodies), suggesting an autoregulatory function similar to that of importin-alpha (show KPNA4 Antibodies).
study presents the crystal structure of the SPN1 (show SSPN Antibodies).CRM1 (show XPO1 Antibodies).RanGTP export complex at 2.5 angstrom resolution (where SPN1 (show SSPN Antibodies) is snurportin1 and RanGTP is guanosine 5' triphosphate-bound Ran
the binding of dimethylated RNA-caps (show CAPS Antibodies) to snurportin 1
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
RNA, U transporter 1
, snurportin 1
, RNA U transporter 1