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anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Antibodies

SHOC2 encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. Additionally we are shipping Soc-2 Suppressor of Clear Homolog (C. Elegans) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SHOC2 56392 O88520
SHOC2 309548 Q6AYI5
SHOC2 8036 Q9UQ13
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Top anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of SHOC2 in human spleen tissue with this product at 5 μg/ml. Western blot analysis of SHOC2 in Jurkat cell lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: SHOC2Antibody Dilution: 1.0ug/mlSample Tissue: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SHOC2 Antibody (N-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow). SHOC2 Antibody (N-term)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SHOC2 antibody detected the SHOC2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.2 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

SHOC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Rat (Rattus) ,


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Top referenced anti-Soc-2 Suppressor of Clear Homolog (C. Elegans) Antibodies

  1. Human Polyclonal SHOC2 Primary Antibody for EIA, IHC (p) - ABIN500706 : Sieburth, Sun, Han: SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. in Cell 1998 (PubMed)
    Show all 4 references for ABIN500706

  2. Human Polyclonal SHOC2 Primary Antibody for EIA, IHC (fro) - ABIN1109005 : Matsunaga-Udagawa, Fujita, Yoshiki, Terai, Kamioka, Kiyokawa, Yugi, Aoki, Matsuda: The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf. in The Journal of biological chemistry 2010 (PubMed)

More Antibodies against Soc-2 Suppressor of Clear Homolog (C. Elegans) Interaction Partners

Mouse (Murine) Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) interaction partners

  1. Data suggest that SUR-8 may act in an ERK (show EPHB2 Antibodies)-independent pathway to regulate AVC development.

  2. Erbin (show ERBB2IP Antibodies) has a regulatory role in the Ras-Raf (show RAF1 Antibodies)-MEK (show MDK Antibodies) pathway and may inhibit ERK (show EPHB2 Antibodies) activation by disrupting the Sur-8-Ras/Raf (show RAF1 Antibodies) interaction

Human Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) interaction partners

  1. results demonstrate that PSMC5 (show PSMC5 Antibodies) is a new and important player involved in regulating ERK1/2 (show MAPK1/3 Antibodies) signal transmission through the remodeling of Shoc2 scaffold complex in a spatially-defined manner.

  2. Noonan-like syndrome has been related to the invariant c.4A > G missense change in SHOC2.

  3. Two unrelated Taiwanese patients have been described with Noonan-like syndrome with loose anagen hair who also have moyamoya disease and in whom heterozygous germline mutation in SHOC2 was found.

  4. ectopic overexpression of human Shoc2 in PC12 cells significantly promotes neurite extension in the presence of Epidermal Growth Factor (show EGF Antibodies), a stimulus that induces proliferation rather than differentiation in these cells.

  5. Extreme phenotypic variability associated with the invariant SHOC2 c.4A>G (p.Ser2Gly) missense mutation in Noonan-like syndrome with loose anagen hair.

  6. A newborn heterozygous for the invariant c.4A>G missense change in SHOC2.

  7. Data show that both Shoc2 and HUWE1 (show HUWE1 Antibodies) are necessary to control the levels and ubiquitination of the Shoc2 signaling partner, RAF-1 (show RAF1 Antibodies).

  8. Both MRAS (show MRAS Antibodies) and SHOC2 play a key role in polarized migration.

  9. SHOC2 and CRAF (show RAF1 Antibodies) mediate ERK1/2 (show MAPK1/3 Antibodies) reactivation in mutant NRAS (show NRAS Antibodies)-mediated resistance to RAF (show RAF1 Antibodies) inhibitor.

  10. targeting of Shoc2 to late endosomes may facilitate EGFR (show EGFR Antibodies)-induced ERK (show EPHB2 Antibodies) activation under physiological conditions of cell stimulation by EGF (show EGF Antibodies), and therefore, may be involved in the spatiotemporal regulation of signaling through the RAS-RAF (show RAF1 Antibodies) module

Soc-2 Suppressor of Clear Homolog (C. Elegans) (SHOC2) Antigen Profile

Protein Summary

This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.

Gene names and symbols associated with SHOC2

  • soc-2 (suppressor of clear) homolog (C. elegans) (Shoc2) antibody
  • soc-2 suppressor of clear homolog (shoc2) antibody
  • soc-2 suppressor of clear homolog (C. elegans) (SHOC2) antibody
  • soc-2 suppressor of clear homolog (C. elegans) (shoc2) antibody
  • AU017287 antibody
  • mKIAA0862 antibody
  • si:ch211-159c12.3 antibody
  • si:ch211-197i12.3 antibody
  • SIAA0862 antibody
  • SOC2 antibody
  • SUR8 antibody
  • zgc:152956 antibody

Protein level used designations for SHOC2

Ras-binding protein SUR-8 , leucine-rich repeat protein SHOC-2 , protein soc-2 homolog , protein sur-8 homolog , suppressor of clear, C. elegans, homolog of , Protein soc-2 homolog , Protein sur-8 homolog

GENE ID SPECIES
56392 Mus musculus
309548 Rattus norvegicus
380042 Xenopus laevis
8036 Homo sapiens
511417 Bos taurus
423894 Gallus gallus
477819 Canis lupus familiaris
555476 Danio rerio
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