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Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Additionally we are shipping Sodium Channel, Nonvoltage-Gated 1, delta Antibodies (70) and many more products for this protein.
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deltabetagamma-ENaC (show SCNN1A Proteins) is inhibited by CFTR (show CFTR Proteins) but activated by cyclic AMP (show APRT Proteins).
delta-ENaC expression is low in NCI-H441, Calu (show CALU Proteins)-3, and ATI cells and does not contribute to transepithelial sodium absorption
study characterized a new variant, delta2 ENaC (show SCNN1A Proteins), in lung epithelial cells; heterologous delta2betagamma ENaC (show SCNN1A Proteins) exhibited a number of divergent features from the delta1betagamma counterpart in biophysics and pharmacology, regulation, and the lifespan of proteins
delta-ENaC undergoes dynamin (show DNM1 Proteins)-independent endocytosis as opposed to alphabetagamma-channels.
These results suggest that COMMD1 downregulates deltaENaC activity by reducing deltaENaC surface expression through promoting internalization of surface deltaENaC to an intracellular recycling pool, possibly via enhanced ubiquitination.
Cpt (show CHPT1 Proteins)-cAMP activates human epithelial sodium channels via relieving self-inhibition.
CPT (show CHPT1 Proteins)-cGMP Stimulates Human Alveolar Fluid Clearance by Releasing External Na+ Self-Inhibition of ENaC (show SCNN1A Proteins).
Data support a physiological role for SGK1.1 in the regulation of delta-ENaC through a pathway that differs from the classical one and suggest that the kinase could serve as an integrator of different signaling pathways converging on the channel.
delta ENaC is regulated by Murr1 (show COMMD1 Proteins)
ENaCdelta activity is regulated by protons, and may contribute to the pH sensation and/or pH regulation in the human brain
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (By similarity).
sodium channel, nonvoltage-gated 1, delta
, amiloride-sensitive sodium channel subunit delta
, epithelial Na(+) channel subunit delta
, nonvoltage-gated sodium channel 1 subunit delta
, sodium channel, voltage-gated, type I, delta polypeptide
, epithelial sodium channel delta subunit