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Sodium Channel, Voltage-Gated, Type III, beta Subunit Proteins (SCN3B)

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. Additionally we are shipping Sodium Channel, Voltage-Gated, Type III, beta Subunit Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCN3B 235281 Q8BHK2
SCN3B 245956 Q9JK00
SCN3B 55800 Q9NY72
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Top Sodium Channel, Voltage-Gated, Type III, beta Subunit Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,284.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,289.83
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,289.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$486.07
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SCN3B Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus)

Human , , ,
, ,

More Proteins for Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Interaction Partners

Mouse (Murine) Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) interaction partners

  1. This study demonistrated that scn3b gene expression in mouse dorsal raphe nucleus

  2. deficiency in Scn3b results in significant atrial electrophysiological and intracardiac conduction abnormalities

  3. SCN3B mediates a p53 (show TP53 Proteins)-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

  4. Bipolar electrogram and monophasic action potential recordings from the ventricles of Langendorff-perfused Scn3b(-/-) hearts demonstrated ventricular tachycardias induced by programmed electrical stimulation.

Human Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) interaction partners

  1. Contribution of Cardiac Sodium Channel (show SCN5A Proteins) beta-Subunit (show POLG Proteins) Variants to Brugada Syndrome.

  2. In a nonreferred nationwide Danish cohort of SIDS (show IDS Proteins) cases, up to 5/66 (7.5%) of SIDS (show IDS Proteins) cases can be explained by genetic variants in the sodium channel complex genes.

  3. SCN1 (show ELANE Proteins)-3B the gene that encode respectively a- and b-subunits of the cardiac fast voltage-gated sodium channel, have been linked to atrial fibrillation.

  4. The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A (show SCN5A Proteins)-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5 (show SCN5A Proteins).

  5. three mutations in SCN3B were investigated electrophysiologically and all led to loss of function in the sodium current, supporting the hypothesis that decreased sodium current enhances atrial fibrillation susceptibility

  6. The researchers found evidence of an association between SCN3B subunit mutations and sudden infant death syndrome pathogenesis.

  7. The sodium channel {beta}3-subunit induces multiphasic gating in NaV1.3 (show SCN3A Proteins) and affects fast inactivation via distinct intracellular regions.

  8. This study identifies the first atrial fibrillation(AF) -associated mutation in SCN3B, and suggests that mutations in SCN3B may be a new pathogenic cause of AF.

  9. Study provides molecular and cellular evidence implicating mutations in SCN3B as a cause of idiopathic ventricular fibrillation.

  10. SCN3B mediates a p53 (show TP53 Proteins)-dependent apoptotic pathway and may be a candidate for gene therapy combined with anticancer drugs.

Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) Protein Profile

Protein Summary

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with SCN3B

  • sodium channel, voltage-gated, type III, beta (SCN3B)
  • sodium channel, voltage-gated, type III, beta (Scn3b)
  • sodium channel, voltage-gated, type III, beta subunit (SCN3B)
  • sodium channel, voltage-gated, type III, beta subunit (Scn3b)
  • 1110001K16Rik protein
  • 4833414B02Rik protein
  • HSA243396 protein
  • SCNB3 protein

Protein level used designations for SCN3B

sodium channel subunit beta-3 , brain and heart sodium channel beta 3 subunit , sodium channel beta 3 subunit , voltage-gated sodium channel beta-3 subunit

GENE ID SPECIES
540925 Bos taurus
235281 Mus musculus
245956 Rattus norvegicus
55800 Homo sapiens
610239 Canis lupus familiaris
100713021 Cavia porcellus
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