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Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Proteins (SCN7A)

SCN7A encodes one of the many voltage-gated sodium channel proteins. Additionally we are shipping Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Antibodies (27) and Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse SCN7A SCN7A 20272  
Rat SCN7A SCN7A 64155  
SCN7A 6332 Q01118
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Top Sodium Channel, Voltage-Gated, Type VII, alpha Subunit Proteins at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SCN7A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Interaction Partners

Mouse (Murine) Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. SAP97 (show DLG1 Proteins) promotes the stability of Nax channels at the plasma membrane.

  2. Nax/Nav2 channel is expressed in alveolar type II cells, suggesting a role in the control of extracellular sodium level.

  3. Nav2-deficient mice show a preference for 0.15 M NaCl over water during a free two-choice intake test compared with wild-type; preference ratios for NaCl in wild tend to increase after combined superior laryngeal and glossopharyngeal nerve transection.

  4. identified the promoter and transcription start sites of Na(x) sodium channel in dorsal root ganglia neurons; findings provide the basis with which to understand tissue-specific regulation of Nax sodium channel gene (Scn7a) expression

Human Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) interaction partners

  1. The authors demonstrated that the sodium channel Nax functions as a sodium sensor. With increased extracellular sodium, Nax up-regulates prostasin (show PRSS8 Proteins), which results in activation of the sodium channel ENaC (show SCNN1A Proteins).

  2. SNP rs7565062 of SCN7A was significantly associated with essential hypertension in a Northern Han Chinese population

Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A) Protein Profile

Protein Summary

This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics\; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels\; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.

Gene names and symbols associated with SCN7A

  • sodium channel, voltage-gated, type VII, alpha (Scn7a)
  • sodium channel, voltage-gated, type VII, alpha subunit (SCN7A)
  • 1110034K09Rik protein
  • AI642000 protein
  • Na-G protein
  • NaG protein
  • Nav2 protein
  • Nav2.1 protein
  • Nav2.2 protein
  • Nav2.3 protein
  • Nax protein
  • SCN6A protein

Protein level used designations for SCN7A

sodium channel, voltage-gated, type VI, alpha polypeptide , sodium channel, voltage-gated, type VII, alpha polypeptide , sodium channel protein type 7 subunit alpha , sodium channel voltage-gated type VI alpha polypeptide , sodium channel, voltage-gated, type 6, alpha polypeptide , putative voltage-gated sodium channel subunit alpha Nax , sodium channel protein cardiac and skeletal muscle subunit alpha , sodium channel protein type VII subunit alpha , voltage-dependent sodium channel alpha subunit

GENE ID SPECIES
20272 Mus musculus
64155 Rattus norvegicus
6332 Homo sapiens
100516881 Sus scrofa
507516 Bos taurus
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