Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A) ELISA Kits

SCN9A encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Additionally we are shipping SCN9A Antibodies (97) and SCN9A Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SCN9A 20274  
SCN9A 78956 O08562
SCN9A 6335 Q15858
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SCN9A ELISA Kits at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 0.1 ng/mL 0.5-10 ng/mL 96 Tests Log in to see 15 to 18 Days
$707.14
Details
Human 0.1 ng/mL 0.5-10 ng/mL 96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Cow
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Dog
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Chicken
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rabbit
96 Tests Log in to see 15 to 18 Days
$707.14
Details
Mouse
96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for SCN9A Interaction Partners

Cow (Bovine) Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A) interaction partners

  1. TNF-alpha (show TNF ELISA Kits) up-regulates NaV1.7 mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha (show TNF ELISA Kits)

  2. Findings suggest that the endothelin-1 (show EDN1 ELISA Kits)-induced down-regulation of NaV1.7 (SCN9A) diminishes NaV1.7-related catecholamine secretion and dephosphorylation of tau.

  3. Nav1.7-Ca2 (show CA2 ELISA Kits)+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK (show MAPK1 ELISA Kits)) and p38 (show MAPK14 ELISA Kits) attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK (show MAPK1 ELISA Kits) and p38 (show MAPK14 ELISA Kits)

  4. constitutively phosphorylated/activated ERK (show MAPK1 ELISA Kits) destabilizes Na(+) channel alpha-subunit (show POLG ELISA Kits) mRNA via translational event, which negatively regulates steady-state level of alpha-subunit (show POLG ELISA Kits) mRNA and cell surface expression of functional Na(+) channels.

  5. Na influx via scn9a converged on inhibitory phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

Mouse (Murine) Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A) interaction partners

  1. the FGF13 (show FGF13 ELISA Kits)/Nav1.7 complex is essential for sustaining the transmission of noxious heat signals

  2. this paper shows that Nav1.7, by coupling with CRMP1 (show CRMP1 ELISA Kits), mediates the axonal retrograde signaling of Sema3A (show SEMA3A ELISA Kits) in axonal guidance

  3. Experiments show that integration of synaptic inputs over time by Nav1.7 is critical for body weight regulation and reveal a mechanism for synaptic control of circuits regulating long term homeostatic functions.

  4. Nav1.7 deletion has profound effects on gene expression, leading to an upregulation of enkephalin precursor Penk (show PENK ELISA Kits) mRNA and met-enkephalin protein in sensory neurons.

  5. Global Nav1.7 knockouts showed no defects in mechanical sensitivity or overall movement yet were completely insensitive to painful tactile, thermal, and chemical stimuli and were anosmic.

  6. Sodium channel Nav1.7, encoded by SCN9A, is expressed in DRG neurons and regulates their excitability.

  7. a novel regulatory mechanism that utilizes CRMP2 (show DPYSL2 ELISA Kits) SUMOylation to choreograph NaV1.7 trafficking.

  8. Behavioural deficits in Nav1.7/Nav1.8 (show SCN10A ELISA Kits) knockout mice reflects a failure of action potential propagation in a mechanosensitive set of sensory neurons rather than a loss of primary transduction currents.

  9. Deleting SCN9A in both sensory and sympathetic neurons abolishes pain sensations.

  10. These results demonstrate increased expression levels of Nav1.7, Nav1.8 (show SCN10A ELISA Kits), and perhaps Nav1.1 (show SCN1A ELISA Kits) in the dorsal root ganglia in mice with a heterozygous mutation of the Nf1 (show NF1 ELISA Kits) gene

Human Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A) interaction partners

  1. the FGF13 (show FGF13 ELISA Kits)/Nav1.7 complex is essential for sustaining the transmission of noxious heat signals

  2. This study showed that gain-of-function attributes at the channel level and differential effects of physiologically relevant thermal stimuli on the excitability of DRG neurons expressing mutant and WT Nav1.7 channels, suggesting a cellular mechanism for warmth-triggered pain episodes in Erythromelalgia patients.

  3. The four congenital insensitivity to pain families, while not closely related, belong to the same ethnic group and clan (show NLRC4 ELISA Kits), and the SCN9A mutation may be specific, if not unique to this group

  4. A novel Nav1.9 (show SCN11A ELISA Kits) mutation, p.Arg222His, was identified in patients with early-onset pain in distal extremities including joints and gastrointestinal disturbances, but was absent from an asymptomatic blood relative.

  5. Gain-of-function mutation of a voltage-gated sodium channel NaV1.7 associated with peripheral pain and impaired limb development

  6. Results indicate that Nav 1.7 promotes gastric cancer progression through MACC1 (show MACC1 ELISA Kits)-mediated upregulation of NHE1 (show SLC9A1 ELISA Kits).

  7. report the engineering of highly potent and selective inhibitors of the Nav1.7 channel based on tarantula ceratotoxin-1 (CcoTx1). We utilized a combination of directed evolution, saturation mutagenesis, chemical modification, and rational drug design to obtain higher potency and selectivity to the Nav1.7 channel

  8. Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of human NaV1.7.

  9. Postoperative pain was affected by SCN9A genetic variability in gynecological surgical patients.

  10. Patients with the SCN9A mutation with inherited erythromelalgia were characterized for the pain phenotype among individuals.

SCN9A Antigen Profile

Antigen Summary

This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder.

Gene names and symbols associated with SCN9A

  • sodium channel, voltage-gated, type IX, alpha subunit (SCN9A) antibody
  • sodium channel, voltage-gated, type IX, alpha (Scn9a) antibody
  • DKFZp459G084 antibody
  • ETHA antibody
  • FEB3B antibody
  • GEFSP7 antibody
  • mKIAA4197 antibody
  • Nav1.7 antibody
  • NE-NA antibody
  • NENA antibody
  • PN1 antibody
  • Scn2a antibody
  • SCN9A antibody
  • SFNP antibody

Protein level used designations for SCN9A

sodium channel, voltage-gated, type IX, alpha subunit , sodium channel protein type 9 subunit alpha-like , peripheral sodium channel 1 , sodium channel 25 , sodium channel protein type 9 subunit alpha , sodium channel protein type IX subunit alpha , sodium channel, voltage-gated, type IX, alpha polypeptide , voltage-gated sodium channel alpha subunit Nav1.7 , voltage-gated sodium channel subunit alpha Nav1.7 , sodium channel, voltage-gated, type 9, alpha polypeptide , hNE-Na , neuroendocrine sodium channel , nas , schwann cell sodium channel , sodium channel alpha-subunit

GENE ID SPECIES
488381 Canis lupus familiaris
533065 Bos taurus
100016648 Monodelphis domestica
100172961 Pongo abelii
100385702 Callithrix jacchus
100482886 Ailuropoda melanoleuca
100516701 Sus scrofa
100583836 Nomascus leucogenys
20274 Mus musculus
78956 Rattus norvegicus
6335 Homo sapiens
100009210 Oryctolagus cuniculus
Selected quality suppliers for SCN9A (SCN9A) ELISA Kits
Did you look for something else?