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anti-Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6) Antibodies

Transports L-glutamate and also L- and D-aspartate. Additionally we are shipping Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 Proteins (5) and Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC1A6 20513 O35544
SLC1A6 84012 O35921
SLC1A6 6511 P48664
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Top anti-Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Anti-EAAT4 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate Lane 3: NRK Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (32.89 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (33.26 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

SLC1A6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 Interaction Partners

Mouse (Murine) Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6) interaction partners

  1. Glutamate (show GRIN1 Antibodies) transporters EAAT4 and EAAT5 (show SLC1A7 Antibodies) are expressed in vestibular hair cells and calyx endings.

  2. The role of EAAT4 in cortical glutamatergic transmission may be more important than previously thought.

  3. Purkinje cell loss in the Inpp4a (show INPP4A Antibodies)(wbl) mutant is due to glutamate (show GRIN1 Antibodies) excitotoxicity initiated by the climbing fiber, and that Eaat4 may exert a protective effect.

  4. abnormal expression of EAAT4, GABRA6 (show GABRA6 Antibodies), Spi2 combined with lower levels of glutamate (show GRIN1 Antibodies) and GABA are likely to be associated with the pathophysiology of Canavan disease.

  5. These results demonstrate that EAAT4 is expressed in astrocytes. This astrocytic localization of neuronal EAAT4 may reveal a new function of EAAT4 in the central nervous system.

  6. EAAT4 mRNA is expressed in the cerebellum of prion protein (show PRNP Antibodies)-deficient (PrP-/-) mice presenting with cerebellar ataxia (show USP14 Antibodies), at the levels identical to those in the cerebellum of non-ataxic PrP+/- mice

  7. EAAT4 is present in the outer segments, a nonsynaptic region of photoreceptors, where it might provide a feedback mechanism for sensing extracellular glutamate (show GRIN1 Antibodies) or serve as an outer barrier to prevent glutamate (show GRIN1 Antibodies) from escaping from the retina.

  8. The main role of EAAT4 is to remove low concentrations of glutamate (show GRIN1 Antibodies) that escape from the uptake by glial transporters at late times and thus prevent the transmitter from spilling over to neighboring synapses.

  9. This result demonstrates that GLAST (show SLC1A3 Antibodies) plays a role in preventing excitotoxic cerebellar damage after ischemia in concert with EAAT4.

  10. The correlation of promoter activity to protein expression makes the EAAT4 BAC promoter reporter a valuable tool to study regulation of EAAT4 expression.

Human Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6) interaction partners

  1. Decreased SLC1A6 expression in neuregulin 1 (show NRG1 Antibodies) risk variant may be an adaptive effect to restore glutamate (show GRIN1 Antibodies) signalling in schizophrenia patients.

  2. A twofold difference in functional EAAT4 levels is sufficient to alter signaling to Bergman glia in reporter mice.

  3. strate-dependent gating of anion channels associated with excitatory amino acid transporter 4.

  4. a conserved aspartate determines pore properties of anion channels associated with excitatory amino acid transporter 4 (EAAT4)

  5. At least one susceptibility locus for schizophrenia may be located within or nearby SLC1A6.

  6. Independent, rather than cooperative anion conductance gating significantly alters predictions of the influence that EAAT4-mediated anion currents will have on synaptic transmission at low glutamate (show GRIN1 Antibodies) concentrations.

  7. conclusion, maximal glutamate (show GRIN1 Antibodies) transport modulation by SGK1 (show SGK1 Antibodies) is accomplished by direct EAAT4 stimulation and to a lesser extent by inhibition of intrinsic Nedd4-2 (show NEDD4L Antibodies).

Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6) Antigen Profile

Protein Summary

Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium (By similarity).

Gene names and symbols associated with SLC1A6

  • solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 (SLC1A6) antibody
  • solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 (slc1a6) antibody
  • solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 (LOC100224299) antibody
  • solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 (Slc1a6) antibody
  • EAAT4 antibody
  • SLC1A6 antibody
  • zgc:171923 antibody

Protein level used designations for SLC1A6

solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 , excitatory amino acid transporter 4 , EAAT1C , EAAT4 , excitatory amino acid transporter SLC1A6 , glastc , excitatory amino acid transporter 4-like , high-affinity neuronal glutamate transporter , sodium-dependent glutamate/aspartate transporter , solute carrier family 1 member 6 , solute carrier family 1, member 6 , high affinity aspartate/glutamate transporter , glutamate transporter

GENE ID SPECIES
420057 Gallus gallus
455789 Pan troglodytes
538673 Bos taurus
559270 Danio rerio
718010 Macaca mulatta
100224299 Taeniopygia guttata
100349456 Oryctolagus cuniculus
100404384 Callithrix jacchus
20513 Mus musculus
84012 Rattus norvegicus
6511 Homo sapiens
403749 Canis lupus familiaris
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